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Lamina lucida information


The lamina lucida is a component of the basement membrane which is found between the epithelium and underlying connective tissue (e.g., epidermis and dermis of the skin). It is a roughly 40 nanometre wide electron-lucent zone between the plasma membrane of the basal cells and the (electron-dense) lamina densa of the basement membrane.[1]

Similarly, electron-lucent and electron-dense zones can be seen between enamel of teeth and the junctional epithelium. The electron-lucent zone is adjacent to the cells of the junctional epithelium and might be considered a continuation of the lamina lucida as both are seen to harbour hemidesmosomes. However, unlike the lamina densa, the electron-dense zone adjacent to enamel show no signs of hemidesmosomes.[2]

Some theorize that the lamina lucida is an artifact created when preparing the tissue, and that the lamina lucida is therefore equal to the lamina densa in vivo.[3]

  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. Page 5. ISBN 0-7216-2921-0.
  2. ^ Lindhe's Clinical Periodontology and Implant Dentistry, 4th ed.
  3. ^ Chan F, Inoue S (1994). "Lamina lucida of basement membrane: an artefact". Microsc Res Tech. 28 (1): 48–59. doi:10.1002/jemt.1070280106. PMID 8061357. S2CID 36363808.

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Lamina lucida

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The lamina lucida is a component of the basement membrane which is found between the epithelium and underlying connective tissue (e.g., epidermis and...

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Basal lamina

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three layers: the lamina lucida (electron-lucent), lamina densa (electron-dense), and lamina fibro-reticularis (electron-lucent). The lamina densa was formerly...

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Lamina densa

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epidermis and dermis of the skin, and is an electron-dense zone between the lamina lucida and dermis, synthesized by the basal cells of the epidermis, and composed...

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Basement membrane

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called the lamina lucida, while the denser-colored layer closer to the connective tissue is called the lamina densa. The electron-dense lamina densa layer...

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Hemidesmosome

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cells connecting the basal epithelial cells to the lamina lucida, which is part of the basal lamina. Hemidesmosomes are also involved in signaling pathways...

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Histology of the vocal cords

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zones, the lamina lucida and lamina densa. The lamina lucida appears as a low density clear zone medial to the epithelial basal cells. The lamina densa has...

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Epidermolysis bullosa

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collagen. This disease is characterized by blister formation within the lamina lucida of the basement membrane zone: 599  and is inherited in an autosomal...

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Suction blister

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published worldwide that support these uses. During suction blistering, the lamina lucida of the skin is cleaved from the underlying layers. This separates the...

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Muscle cell

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covered by a lamina coat which is approximately 50  nm wide. The laminar coat is separable into two layers; the lamina densa and lamina lucida. In between...

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Skin secretions

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Stratum spinosum Malpighian layer Stratum basale Basement membrane Basal keratinocyte Lamina lucida Lamina densa Dermis Papillary Dermal papillae Reticular...

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Pemphigoid

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BP230 (BPAg1) and BP180 (BPAg2 or type XVII collagen), located in the lamina lucida of the basement membrane zone. These antigens play an important role...

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Mucous membrane pemphigoid

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Diagnostic techniques: antibodies (IgG) precipitate complement (C3) in the lamina lucida of the basement membrane. Circulating auto-antibodies to BP-1 antigen...

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Junctional epithelium

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internal basal lamina consists of a lamina lucida and lamina densa. This internal basal lamina of the EA is continuous with the external basal lamina between...

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Ladinin 1

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(1998). "97 kDa linear IgA bullous dermatosis antigen localizes in the lamina lucida between the NC16A and carboxyl terminal domains of the 180 kDa bullous...

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Uterine epithelium

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epithelial cells produce the basal lamina on which they rest. The basal lamina is composed of two regions; the lamina lucida that is an electron lucent layer...

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Linear IgA bullous dermatosis

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the 97 kDa component of BPAG2 (bullous pemphigoid antigen 2) in the lamina lucida are the primary cause of linear IgA bullous dermatosis (LABD). The most...

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and integrins. Ideally, the basement membrane must contain a lamina lucida and a lamina densa. Stratified squamous epithelium: is simulated by oral keratinocytes...

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List of target antigens in pemphigoid

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Laminin 332) Linear IgA bullous dermatosis LAD1 portion of BPAG2 Collagen type VII 97 290/145 Protein 105 pemphigoid Protein in lower lamina lucida 105...

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Clubiona

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C. longipes Nicolet, 1849 – Chile C. luapalana Giltay, 1935 – Congo C. lucida He, Liu & Zhang, 2016 – China C. ludhianaensis Tikader, 1976 – India, Bangladesh...

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Hololepta lamina Paykull, 1811 Hololepta lata (Marseul, 1853) Hololepta liebmanni Bickhardt, 1921 Hololepta lissopyga Marseul, 1853 Hololepta lucida J. E....

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(Anchoa ischana) Big-eye anchovy (Anchoa lamprotaenia) Bright anchovy (Anchoa lucida) Shortfinger anchovy (Anchoa lyolepis) Common anchovy (Anchoa mitchilli)...

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(Blanchard, 1848) Fiery copper, Paralucia pyrodiscus (Doubleday, 1847) P. p. lucida (Crosby, 1951) Purple or Bathurst copper, Paralucia spinifera (Edwards &...

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List of Clubionidae species

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C. longipes Nicolet, 1849 — Chile C. luapalana Giltay, 1935 — Congo C. lucida He, Liu & Zhang, 2016 — China C. ludhianaensis Tikader, 1976 — India, Bangladesh...

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