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Kindling hypothesis information


Kindling hypothesis is the argument that some neurological and psychiatric conditions worsen due to repeated episodes of symptoms that cause neurological changes. These theories posit that if episodes continue without treatment, the threshold to trigger an epileptic seizure or mood episode in bipolar disorder will be lowered.[1]

  • Kindling hypothesis of bipolar disorder, see biology of bipolar disorder
  • Kindling hypothesis of depression
  • Kindling model of epilepsy
  • Kindling (sedative–hypnotic withdrawal), for GABAnergic drugs
  1. ^ Post, Robert M. (2016). "The kindling/sensitization model and the pathophysiology of bipolar disorder". Bipolar Disorders: Basic Mechanisms and Therapeutic Implications (3 ed.). Cambridge University Press. pp. 204–218. ISBN 978-1-107-06271-9.

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Kindling hypothesis

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Kindling hypothesis is the argument that some neurological and psychiatric conditions worsen due to repeated episodes of symptoms that cause neurological...

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Kindling hypothesis of depression

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The kindling hypothesis of depression posits that each period of depression in someone with major depressive disorder (MDD) causes neurological changes...

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Auditory hallucination

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published study, "Hearing Voices in Different Cultures: A Social Kindling Hypothesis" compared the experiences of three groups of 20 participants who...

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Psychosis

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(October 2015). "Hearing Voices in Different Cultures: A Social Kindling Hypothesis". Topics in Cognitive Science. 7 (4): 646–663. doi:10.1111/tops.12158...

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Bipolar disorder

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sensitivity of these circuits causes depression. According to the "kindling" hypothesis, when people who are genetically predisposed toward bipolar disorder...

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Biology of bipolar disorder

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been drawn between bipolar disorder and epilepsy, supporting the kindling hypothesis, this model is generally not supported by studies directly assessing...

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Alcohol withdrawal syndrome

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misuse and kindling via multiple alcohol withdrawals may lead to permanent alterations in the GABAA receptors. The mechanism behind kindling is sensitization...

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Lucretius

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theorised, there followed the development in turn of crude huts, use and kindling of fire, clothing, language, family, and city-states. He believed that...

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Thor Heyerdahl

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dug a defensive moat on the eastern end of the island and filled it with kindling. During the uprising, Heyerdahl claimed, the "Long Ears" ignited their...

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Fibromyalgia

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pathways that regulate mood and pain. Eventually, a sensitization and kindling effect occurs in certain neurons leading to the establishment of fibromyalgia...

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Granule cell dispersion

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different animal models, such as the kainic acid model, pilocarpine model, and kindling model. But granule cell dispersion was not found by using perforant pathway...

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Substantia nigra

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pattern, and drug sensitivity of putative GABAergic nigral neurons in the kindling model of epilepsy". The European Journal of Neuroscience. 20 (9): 2377–86...

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Gavari

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chanting, madal drum and thali cymbal music, a Shaivite trishula, and the kindling of a dhuni fire. Initial sanction invocations are usually held in a darkened...

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Delirium tremens

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constipation (OIC) SUD Opioid use disorder (OUD) Sedative / hypnotic SID Kindling (sedative–hypnotic withdrawal) benzodiazepine: SID Benzodiazepine overdose...

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Heraclitus

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man did create, but it ever was and is and will be: ever-living fire, kindling in measures and being quenched in measures. This is the oldest extant quote...

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Fossil record of fire

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dominant component of many ecosystems, around 6 to 7 million years ago; this kindling provided tinder which allowed for the more rapid spread of fire. These...

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Carl Faingold

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to periaqueductal gray pathway: Plastic changes induced by audiogenic kindling and reversal by gabapentin. Brain Res. 1475:71-79, 2012. 112. Faingold...

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Fire

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dominant component of many ecosystems, around 6 to 7 million years ago; this kindling provided tinder which allowed for the more rapid spread of fire. These...

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Alcoholism

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episodes. The kindling effect leads to persistent functional changes in brain neural circuits as well as to gene expression. Kindling also results in...

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Risk factors of schizophrenia

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deficiency in some cases. There is evidence that excessive alcohol use via a kindling mechanism can occasionally cause the development of chronic substance-induced...

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Tramadol

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effects of tramadol, its enantiomers and its M1 metabolite in the rat kindling model of epilepsy". British Journal of Pharmacology. 131 (2): 203–212....

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Urban riot

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Ohio, US, Residents at forum named poverty, above other causes, as the kindling for the riot. 2005 Birmingham riots 22 October 2005, Birmingham, England...

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Cosmos and Psyche

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opined, In the last ten years, landmark works...have been reflecting and kindling a growing awareness that nature is not merely a sum of molecules obeying...

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Lingam

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exists in the kindling stick in a latent form, may not be seen, yet its linga is not destroyed but be seized again by another kindling stick. Fire in...

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Tonal memory

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Musician (2nd Edition). ISBN 978-0-9629496-7-8. Haroutounian, Joanne (2002). Kindling the Spark : Recognizing and Developing Musical Talent. ISBN 978-0-19-512948-9...

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Benzodiazepine withdrawal syndrome

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glutamate excitatory activity during withdrawal may lead to sensitization or kindling of the CNS, possibly leading to worsening cognition and symptomatology...

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Soluble NSF attachment protein

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"Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm". Epilepsy Research. 73 (3): 266–274. doi:10.1016/j.eplepsyres...

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