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Internal ribosome entry site information


An internal ribosome entry site, abbreviated IRES, is an RNA element that allows for translation initiation in a cap-independent manner, as part of the greater process of protein synthesis. Initiation of eukaryotic translation nearly always occurs at and is dependent on the 5' cap of mRNA molecules, where the translation initiation complex forms and ribosomes engage the mRNA. IRES elements, however allow ribosomes to engage the mRNA and begin translation independently of the 5' cap.

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Internal ribosome entry site

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An internal ribosome entry site, abbreviated IRES, is an RNA element that allows for translation initiation in a cap-independent manner, as part of the...

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Cripavirus internal ribosome entry site

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The Cripavirus internal ribosome entry site (CrPV IRES) is an RNA element required for the production of capsid proteins through ribosome recruitment to...

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Hepatitis C virus internal ribosome entry site

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The Hepatitis C virus internal ribosome entry site, or HCV IRES, is an RNA structure within the 5'UTR of the HCV genome that mediates cap-independent translation...

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GJA1

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connexin-43 internal ribosome entry site is an RNA element present in the 5' UTR of the mRNA of GJA1. This internal ribosome entry site (IRES) allows...

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Kozak consensus sequence

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with the ribosomal binding site (RBS), that being either the 5′ cap of a messenger RNA or an internal ribosome entry site (IRES). The Kozak sequence was...

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Ribosome

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phosphorylation. Arabidopsis, Viral internal ribosome entry sites (IRESs) may mediate translations by compositionally distinct ribosomes. For example, 40S ribosomal...

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Five prime untranslated region

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IRES sites. Viral (as well as some eukaryotic) 5′ UTRs contain internal ribosome entry sites, which is a cap-independent method of translational activation...

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GJB1

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entry on Charcot-Marie-Tooth Neuropathy X Type 1 OMIM entries on Charcot-Marie-Tooth Neuropathy X Type 1 Page for Connexin-32 internal ribosome entry...

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Rhopalosiphum padi virus

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intestine virus and Drosophila C virus. Its 5'UTR region contains an internal ribosome entry site (IRES) element with a cross-kingdom activity. It can function...

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