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Intensive insulin therapy information


Intensive insulin therapy or flexible insulin therapy is a therapeutic regimen for diabetes mellitus treatment. This newer approach contrasts with conventional insulin therapy. Rather than minimize the number of insulin injections per day (a technique which demands a rigid schedule for food and activities), the intensive approach favors flexible meal times with variable carbohydrate as well as flexible physical activities. The trade-off is the increase from 2 or 3 injections per day to 4 or more injections per day, which was considered "intensive" relative to the older approach. In North America in 2004, many endocrinologists prefer the term "flexible insulin therapy" (FIT) to "intensive therapy" and use it to refer to any method of replacing insulin that attempts to mimic the pattern of small continuous basal insulin secretion of a working pancreas combined with larger insulin secretions at mealtimes. The semantic distinction reflects changing treatment.

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Intensive insulin therapy

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Intensive insulin therapy or flexible insulin therapy is a therapeutic regimen for diabetes mellitus treatment. This newer approach contrasts with conventional...

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Conventional insulin therapy

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Conventional insulin therapy is a therapeutic regimen for treatment of diabetes mellitus which contrasts with the newer intensive insulin therapy. This older...

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Insulin shock therapy

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Insulin shock therapy or insulin coma therapy was a form of psychiatric treatment in which patients were repeatedly injected with large doses of insulin...

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Insulin pump

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insulin pump is an alternative to multiple daily injections of insulin by insulin syringes or an insulin pen and allows for flexible insulin therapy when...

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Diabetes medication

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Donner T, Sarkar S (2000). "Insulin – Pharmacology, Therapeutic Regimens, and Principles of Intensive Insulin Therapy". In Feingold KR, Anawalt B, Boyce...

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Stress hyperglycemia

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randomized control trial of 1200 medical ICU patients found that intensive insulin therapy significantly reduced morbidity but not mortality among all patients...

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Type 1 diabetes

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working hypothesis intensive insulin therapy has attempted to mimic natural insulin secretion profiles in exogenous insulin infusion therapies. In young people...

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Minimed Paradigm

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T., Schutze J., Hansen B. (1997). "Effect of patient-selected intensive insulin therapy on quality of life". Patient Education and Counseling. 38 (2):...

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Glossary of diabetes

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umbilicus, and other areas. This occurs due to insulin spillover (from excessive production due to obesity or insulin resistance) into the skin which results...

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Type 2 diabetes

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is advised; however, this may not be needed in those who are not on insulin therapy. Bariatric surgery often improves diabetes in those who are obese....

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Diabetes management

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absolute deficiency of insulin require insulin replacement therapy, which is given through injections or an insulin pump. Insulin resistance, in contrast...

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Acromegaly

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hormone after a person has consumed a glucose solution, or by measuring insulin-like growth factor I in the blood. After diagnosis, medical imaging of...

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Complications of diabetes

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foot syndrome (Diabetic amyotrophy) and myocardial infarctions. Intensive insulin therapy is recommended to reduce neuropathy risk, while oral antidiabetic...

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Greet Van den Berghe

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Patrick; Lauwers, Peter; Bouillon, Roger (8 November 2001). "Intensive Insulin Therapy in Critically Ill Patients". New England Journal of Medicine....

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Diabetic ketoacidosis

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"Alberti regime") insulin, phosphate supplementation, need for a loading dose of insulin, and the appropriateness of using bicarbonate therapy in moderate DKA...

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Diabetes

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type 1 and type 2. The most common treatment for type 1 is insulin replacement therapy (insulin injections), while anti-diabetic medications (such as metformin...

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Lipotoxicity

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treatments for lipotoxicity in renal cells are fibrate therapy and intensive insulin therapy. An excess of free fatty acids in liver cells plays a role...

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Hypoglycemia

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common cause of hypoglycemia is medications used to treat diabetes such as insulin, sulfonylureas, and biguanides. Risk is greater in diabetics who have eaten...

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Metformin

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glibenclamide and metformin in type 2 diabetes mellitus patients on insulin therapy". The Journal of the Association of Physicians of India. 51: 1061–4...

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Hydroxyethyl starch

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Meier-Hellmann A, Ragaller M, Weiler N, et al. (January 2008). "Intensive insulin therapy and pentastarch resuscitation in severe sepsis". The New England...

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Donislecel

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despite intensive diabetes management and education. The primary mechanism of action of donislecel is believed to be the secretion of insulin by the infused...

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Critical illness polyneuropathy

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(2007). "Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit". Am. J. Respir...

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Growth hormone therapy

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JR, Manhem P, Groop L (April 2003). "Growth hormone replacement therapy induces insulin resistance by activating the glucose-fatty acid cycle". J. Clin...

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Gestational diabetes

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abnormal glucose levels during fasting and/or after meals; additional therapy with insulin or other medications is required Diabetes which existed prior to...

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Sulfonylurea

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antidiabetic drugs cannot be used either under these circumstances, insulin therapy is typically recommended during pregnancy and in liver and kidney failure...

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Sepsis

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Some people might benefit from tight control of blood sugar levels with insulin. The use of corticosteroids is controversial, with some reviews finding...

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