Nucleic acid melting curve showing hyperchromicity as a function of temperature
Hyperchromicity is the increase of absorbance (optical density) of a material. The most famous example is the hyperchromicity of DNA that occurs when the DNA duplex is denatured.[1] The UV absorption is increased when the two single DNA strands are being separated, either by heat or by addition of denaturant or by increasing the pH level. The opposite, a decrease of absorbance is called hypochromicity.
^Ackerman, Megan M.; Ricciardi, Christopher; Weiss, David; Chant, Alan; Kraemer-Chant, Christina M. (2016). "Analyzing Exonuclease-Induced Hyperchromicity by UV Spectroscopy: An Undergraduate Biochemistry Laboratory Experiment". Journal of Chemical Education. 93 (12): 2089–2095. Bibcode:2016JChEd..93.2089A. doi:10.1021/acs.jchemed.6b00095.
Hyperchromicity is the increase of absorbance (optical density) of a material. The most famous example is the hyperchromicity of DNA that occurs when...
iron deficiency) due to a calculation artifact. MCHC can be elevated ("hyperchromic") in hereditary spherocytosis, sickle cell disease and homozygous hemoglobin...
anemias. RBCs are either normochromic or hypochromic. They are never "hyperchromic". If more than the normal amount of hemoglobin is made, the cells get...
begins to dissociate leading to a rise in the absorbance intensity, hyperchromicity. The temperature at which 50% of DNA is denatured is known as the melting...
with lack of genetic diversity. The affected eye may be hyperpigmented (hyperchromic) or hypopigmented (hypochromic). In humans, an increase of melanin production...
terminal phase, consists of reduction of oligonucleotides, causing a hyperchromic shift in the UV data. DNase I predominantly targets double-stranded DNA...
Primary anemia may refer to: Hyperchromic anemia or chlorosis Pernicious anemia This disambiguation page lists articles associated with the title Primary...
itself on the intestinal wall to feed on the host's blood, and can cause hyperchromic anemia, emaciation, diarrhea, and possibly death. Toxocara canis, a hookworm...
reduced locomotion; exaggerated response to novelty; and densely packed, hyperchromic hippocampal neurons with altered glutamate receptors and transporters...
nucleotides. The third phase, which is the terminal phase, consists of hyperchromic shift resulting from reduction of oligonucleotides. There are several...
They often go away on their own and may regress leaving behind some hyperchromic macules. Histological analysis reveals a monomorphous, devoid of foamy...
“saddle” shape. Tetraanthraporphyrin exhibit strongly red-shifted and hyperchromic absorption bands. The maximum of absorption is about 830 nm. The molar...
extension, intramedullary extension, periosteal reaction and presence of hyperchromic epithelial cells under the microscope.[citation needed] Osteofibrous...
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