Hydroxycarboxylicacidreceptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene...
Hydroxycarboxylicacidreceptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation...
Hydroxycarboxylicacidreceptor 1 (HCA1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1...
L-lactic acid is the primary endogenous agonist of hydroxycarboxylicacidreceptor 1 (HCA1), which is a Gi/o-coupled G protein-coupled receptor (GPCR)....
butyric acid is one of two primary endogenous agonists of human hydroxycarboxylicacidreceptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor. Butyric...
(also known as hydroxycarboxylicacidreceptor 3, HCA3, niacin receptor 2, and NIACR2) binds and is activated by the medium-chain fatty acid, 3-hydroxyoctanoate...
activation of G protein-coupled receptors, including hydroxycarboxylicacidreceptor 2 (HCA2)and hydroxycarboxylicacidreceptor 3 (HCA3), which are highly...
glutamate receptors, such as NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), and kainate receptors, have distinct...
FFAR4 are activated by certain fatty acids that are 6 to more than 21 carbon atoms long. Hydroxycarboxylicacidreceptor 2 is also activated by a SC-FA that...
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
lysophosphatidic acidreceptors (LPARs) are a group of G protein-coupled receptors for lysophosphatidic acid (LPA) that include: Lysophosphatidic acidreceptor 1 (LPAR1;...
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...
only the transmembrane regions of the receptors are considered, amino acid similarity between the two receptor subtypes is approximately 68%. In addition...
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the...
TAS1R1+TAS1R3 heterodimer receptor functions as an umami receptor, responding to L-amino acid binding, especially L-glutamate. The umami taste is most...
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
from a common ancestral receptor. In fact, relatively minor mutations, such as a change in 3 amino acids in many of these receptors can convert a cation-selective...
Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin...
involve FFAR2, e.g., they activate FFAR3, GPR109A (now termed hydroxycarboxylicacidreceptor 2 or HCA2), and two other GPRs, Olfr78 and Olfr558. Most of...
tetrahydrocannabinol. The receptor was identified among cDNAs based on its similarity in amino-acid sequence to the cannabinoid receptor 1 (CB1) receptor, discovered...
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