Hydroxycarboxylicacidreceptor 1 (HCA1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1...
Hydroxycarboxylicacidreceptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene...
Hydroxycarboxylicacidreceptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation...
L-lactic acid is the primary endogenous agonist of hydroxycarboxylicacidreceptor 1 (HCA1), which is a Gi/o-coupled G protein-coupled receptor (GPCR)....
butyric acid is one of two primary endogenous agonists of human hydroxycarboxylicacidreceptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor. Butyric...
(also known as hydroxycarboxylicacidreceptor 3, HCA3, niacin receptor 2, and NIACR2) binds and is activated by the medium-chain fatty acid, 3-hydroxyoctanoate...
activation of G protein-coupled receptors, including hydroxycarboxylicacidreceptor 2 (HCA2)and hydroxycarboxylicacidreceptor 3 (HCA3), which are highly...
glutamate receptors, such as NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), and kainate receptors, have distinct...
FFAR4 are activated by certain fatty acids that are 6 to more than 21 carbon atoms long. Hydroxycarboxylicacidreceptor 2 is also activated by a SC-FA that...
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
lysophosphatidic acidreceptors (LPARs) are a group of G protein-coupled receptors for lysophosphatidic acid (LPA) that include: Lysophosphatidic acidreceptor 1 (LPAR1;...
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain...
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the...
only the transmembrane regions of the receptors are considered, amino acid similarity between the two receptor subtypes is approximately 68%. In addition...
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...
TAS1R1+TAS1R3 heterodimer receptor functions as an umami receptor, responding to L-amino acid binding, especially L-glutamate. The umami taste is most...
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
involve FFAR2, e.g., they activate FFAR3, GPR109A (now termed hydroxycarboxylicacidreceptor 2 or HCA2), and two other GPRs, Olfr78 and Olfr558. Most of...
from a common ancestral receptor. In fact, relatively minor mutations, such as a change in 3 amino acids in many of these receptors can convert a cation-selective...
tetrahydrocannabinol. The receptor was identified among cDNAs based on its similarity in amino-acid sequence to the cannabinoid receptor 1 (CB1) receptor, discovered...