HSPA2 information

HSPA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3I33, 4FSV, 5FPM, 5FPN, 5FPD, 5FPE
Identifiers
Aliases	HSPA2, HSP70-2, HSP70-3, heat shock protein family A (Hsp70) member 2
External IDs	OMIM: 140560 MGI: 96243 HomoloGene: 68564 GeneCards: HSPA2
Gene location (Human)
Chr.	Chromosome 14 (human)
End	64,546,173 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	76,453,712 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; middle frontal gyrus; ; subthalamic nucleus; ; external globus pallidus; ; medulla oblongata; ; internal globus pallidus; ; superior vestibular nucleus; ; corpus callosum; ; inferior olivary nucleus; ; pons;
	Top expressed in
	seminiferous tubule; ; spermatocyte; ; spermatid; ; ascending aorta; ; aortic valve; ; piriform cortex; ; hippocampus proper; ; supraoptic nucleus; ; olfactory epithelium; ; visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; unfolded protein binding; protein binding; enzyme binding; ATP binding; disordered domain specific binding; glycolipid binding; ATPase activity; heat shock protein binding; protein folding chaperone activity; tau protein binding; chaperone binding; misfolded protein binding;
Cellular component	cytoplasm; cytosol; blood microparticle; membrane; spindle; extracellular exosome; cytoskeleton; nucleus; synaptonemal complex; male germ cell nucleus; mitochondrion; cell surface; CatSper complex; myelin sheath; meiotic spindle; plasma membrane;
Biological process	cell differentiation; negative regulation of inclusion body assembly; response to heat; response to unfolded protein; protein refolding; spermatogenesis; response to cold; positive regulation of protein phosphorylation; male meiotic nuclear division; male meiosis I; spermatid development; positive regulation of ATP-dependent activity; synaptonemal complex disassembly; positive regulation of ATPase-coupled calcium transmembrane transporter activity; positive regulation of G2/M transition of mitotic cell cycle; vesicle-mediated transport; cellular response to heat; Unfolded Protein Response; chaperone cofactor-dependent protein refolding;
	Sources:Amigo / QuickGO
Orthologs
	3306
	15512
	ENSG00000126803
	ENSMUSG00000059970
	P54652
	P17156
	NM_021979; NM_001387931
	NM_001002012; NM_008301
	NP_068814
	NP_001002012; NP_032327
	Wikidata
View/Edit Human	View/Edit Mouse

Heat shock-related 70 kDa protein 2 is a protein that in humans is encoded by the HSPA2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000126803 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059970 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: HSPA2 heat shock 70kDa protein 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000126803 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000059970 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: HSPA2 heat shock 70kDa protein 2".

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