HOXA3 information

HOXA3
Identifiers
Aliases	HOXA3, HOX1, HOX1E, homeobox A3
External IDs	OMIM: 142954; MGI: 96175; HomoloGene: 40725; GeneCards: HOXA3; OMA:HOXA3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	27,152,581 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	52,190,316 bp
RNA expression pattern
	Top expressed in
	caput epididymis; ; corpus epididymis; ; right uterine tube; ; left uterine tube; ; parietal pleura; ; renal medulla; ; tibia; ; visceral pleura; ; gastric mucosa; ; transverse colon;
	Top expressed in
	ascending aorta; ; aortic valve; ; tunica albuginea of testis; ; thyroid gland; ; rete testis; ; left lung lobe; ; tracheobronchial tree; ; trachea; ; intercostal muscle; ; pharynx;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity; HMG box domain binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleoplasm; nucleus;
Biological process	embryonic skeletal system morphogenesis; glossopharyngeal nerve morphogenesis; regulation of transcription, DNA-templated; thymus development; transcription, DNA-templated; embryonic skeletal system development; multicellular organism development; animal organ formation; blood vessel remodeling; thyroid gland development; cartilage development; parathyroid gland development; angiogenesis; positive regulation of cell population proliferation; animal organ morphogenesis; specification of animal organ position; anterior/posterior pattern specification; regulation of transcription by RNA polymerase II; calcium ion transport; gene expression; magnesium ion homeostasis; bone mineralization; negative regulation of calcium ion transport; phosphate ion homeostasis; calcium ion homeostasis; positive regulation of receptor binding; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3200
	15400
	ENSG00000105997
	ENSMUSG00000079560
	O43365
	P02831
	NM_030661; NM_153631; NM_153632
	NM_010452
	NP_109377; NP_705895
	NP_034582
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-A3 is a protein that in humans is encoded by the HOXA3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000105997 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000079560 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXA3 homeobox A3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000105997 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000079560 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (July 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (November 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXA3 homeobox A3".

HOXA3 information

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HOXA3

Homeobox

Hox gene

List of human transcription factors

Thymic epithelial cell

PTPRT