Trifunctional enzyme subunit beta, mitochondrial (TP-beta) also known as 3-ketoacyl-CoA thiolase, acetyl-CoA acyltransferase, or beta-ketothiolase is an enzyme that in humans is encoded by the HADHB gene.[5]
HADHB is a subunit of the mitochondrial trifunctional protein and has thiolase activity.
^ abcGRCh38: Ensembl release 89: ENSG00000138029 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000059447 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein)".
humans is encoded by the HADHB gene. HADHB is a subunit of the mitochondrial trifunctional protein and has thiolase activity. The HADHB gene is located on chromosome...
ATP6AP2. The level of renin mRNA appears to be modulated by the binding of HADHB, HuR and CP1 to a regulatory region in the 3' UTR. The gene for renin, REN...
thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit HADHB: hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme...
is a hetero-octamer composed of four alpha and four beta subunits: HADHA HADHB The three functions are 2-enoyl coenzyme A (CoA) hydratase, long-chain 3-hydroxy...
trifunctional protein deficiency is based on mutations in the HADHA and HADHB genes which cause this disorder. These genes each provide instructions for...
present. The alpha subunit catalyzes this reaction, and is attached to HADHB, which catalyzes the last step of the reaction. Mutations in this gene result...
PMID 12890803. Adams DJ, Beveridge DJ, van der Weyden L, et al. (2004). "HADHB, HuR, and CP1 bind to the distal 3'-untranslated region of human renin mRNA...