FAST kinase domain-containing protein 3 (FASTKD3) is a protein that in humans is encoded by the FASTKD3 gene on chromosome 5.[5][6] This protein is part of the Fas-activated serine/threonine kinase domain (FASTKD) containing protein family, which is known for regulating the energy balance of mitochondria under stress.[7][8]
^ abcGRCh38: Ensembl release 89: ENSG00000124279 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000021532 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^UniProt: Q9NYY8
^"Entrez Gene: FAST kinase domains 2".
^Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduña A, Anderson P (Oct 2010). "Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration". Biochemical and Biophysical Research Communications. 401 (3): 440–6. doi:10.1016/j.bbrc.2010.09.075. PMC 2963690. PMID 20869947.
^Yeung KT, Das S, Zhang J, Lomniczi A, Ojeda SR, Xu CF, Neubert TA, Samuels HH (Jun 2011). "A novel transcription complex that selectively modulates apoptosis of breast cancer cells through regulation of FASTKD2". Molecular and Cellular Biology. 31 (11): 2287–98. doi:10.1128/MCB.01381-10. PMC 3133243. PMID 21444724.
FAST kinase domain-containing protein 3 (FASTKD3) is a protein that in humans is encoded by the FASTKD3 gene on chromosome 5. This protein is part of the...
FAM114A2 FAM71B: encoding protein Family with sequence similarity 71 member B FASTKD3: FAST kinase domain-containing protein 3 FBXL7: F-box/LRR-repeat protein...
is oriented on the minus strand. Neighboring genes of C5orf49 include, FASTKD3, MTRR, and ADCY2. C5orf49 has one upstream promoter, GXP_1271072, that...
breast and prostate cancer cells. FASTKD2 has been shown to interact with FASTKD3. The FASTKD2 gene has been observed to bind the DIF-1 complex. GRCh38:...