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H antigen information


H antigen can refer to one of various types of antigens having diverse biological functions:

  • Also known as substance H, H antigen is a precursor to each of the ABO blood group antigens, apparently present in all people except those with the Bombay Blood phenotype[1] (see hh blood group). The gene responsible for making H antigen is FUT1, located on the 19th chromosome in humans
  • Histocompatibility antigen, a major factor in graft rejection. Even when Major Histocompatibility Complex genotype is perfectly matched, can cause slow rejection of a graft.[2]
    • major H antigens "encode molecules that present foreign peptides to T cells"[2]
    • minor H antigens "present polymorphic self peptides to T cells".[2] Includes, e.g. the H-Y antigen
  • a bacterial flagellar antigen[3]
  1. ^ Science Of Biogenetics (18 December 2023). "Do you Know Bombay Blood Group".
  2. ^ a b c Janeway, Charles A. (2001). Immunobiology the immune system health & disease (5. ed.). New York: Garland. ISBN 978-0-8153-3642-6. Retrieved 16 December 2013.
  3. ^ Farlex. "antigen". The Free Dictionary. Retrieved 16 December 2013.

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H antigen

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H antigen can refer to one of various types of antigens having diverse biological functions: Also known as substance H, H antigen is a precursor to each...

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Hh blood group

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substance H), the antigen which is present in blood group O. As a result, they cannot make A antigen (also called substance A) or B antigen (substance...

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Lewis antigen system

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responsible for the presence of soluble A, B and H antigens in bodily fluids. There are two main types of Lewis antigens, Lewis a (Le-a) and Lewis b (Le-b). There...

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Oligosaccharide

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serves as a precursor for the A and B antigen. Therefore, a person with A blood type will have the A antigen and H antigen present on the glycolipids of the...

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Serotype

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whereas the antigen H is tested with a bacterial suspension from a broth culture. The scheme classifies the serovar depending on its antigen formula obtained...

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Pathogenic Escherichia coli

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in animals, namely:[citation needed] O antigen: part of lipopolysaccharide layer K antigen: capsule H antigen: flagellin For example, E. coli strain EDL933...

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ABO blood group system

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is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes. For human blood transfusions, it is the most important...

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Secretor status

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antigens; the FUT1 or H gene, which controls expression of the H antigen, the precursor of ABO antigens; and the secretor gene, FUT2 or Se. All of these genes...

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Blood type

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absence of antibodies and inherited antigenic substances on the surface of red blood cells (RBCs). These antigens may be proteins, carbohydrates, glycoproteins...

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Antigen presentation

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cells recognize only fragmented antigens displayed on cell surfaces, antigen processing must occur before the antigen fragment can be recognized by a...

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Rh blood group system

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someone who is A+ has the A antigen and Rh(D) antigen, whereas someone who is A− has the A antigen but lacks the Rh(D) antigen). The terms Rh factor, Rh...

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Fucose

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termini linked α-1,2 to galactose forms the H antigen, the substructure of the A and B blood group antigens. Fucose is released from fucose-containing...

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MNS antigen system

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antigen system is a human blood group system based upon two genes (glycophorin A and glycophorin B) on chromosome 4. There are currently 50 antigens in...

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Duffy antigen system

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Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is...

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Carcinoembryonic antigen

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Carcinoembryonic antigen (CEA) describes a set of highly-related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal...

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Globo H

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Globo H (globohexaosylceramide) is a globo-series glycosphingolipid antigen that is present on the outer membrane of some cancer cells. Globo H is not...

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CAR T cell

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In biology, chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor...

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Human leukocyte antigen

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The human leukocyte antigen (HLA) system or complex of genes on chromosome 6 in humans which encode cell-surface proteins responsible for regulation of...

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Glycosyltransferase

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of H antigen, producing the A antigen. The B allele encodes 1-3-galactosyltransferase that joins α-D-galactose bonded to D-galactose end of H antigen, creating...

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Glycolipid

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the surface of red blood cells, which acts as an antigen. The unmodified antigen, called the H antigen, is the characteristic of type O, and is present...

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