In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on light microscopy. The cytoplasm's granular homogeneous eosinophilic staining is caused by the presence of HBsAg.
The appearance is classically associated with abundant hepatitis B antigen in the endoplasmic reticulum, but may also be drug-induced.[1][2] In the context of hepatitis B, GGHs are only seen in chronic infections, i.e. they are not seen in acute hepatitis B.
GGHs were first described by Hadziyannis et al.[2][3]
^Cohen, C (Aug 1975). ""Ground-glass" hepatocytes". S Afr Med J. 49 (34): 1401–3. PMID 1162516.
In liver pathology, a groundglasshepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on...
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pathologic appearance of a large bile duct hamartoma. Cholestasis Groundglasshepatocyte Mallory body Sheikh, Abdul Ahad E; Nguyen, Anthony P; Leyba, Katarina;...
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Jean-Pierre; Borisch, Bettina; Hadengue, Antoine; Negro, Francesco (2000). "Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3". Journal...
surface wound but causing internal injury and internal bleeding. For a glass foreign body, "frequently, an innocent skin wound disguises the extensive...
electron microscopy: a quantitative and qualitative study on isolated hepatocytes". Journal of Microscopy. 137 (Pt 2): 189–207. doi:10.1111/j.1365-2818...
the liver, where they invade hepatocytes. They grow and divide in the liver for 2–10 days, with each infected hepatocyte eventually harboring up to 40...
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has been proposed that certain computed tomography findings such as ground-glass opacities, air bronchogram, spiculated margins, vascular convergence...
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