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Glycopeptide antibiotic information


Glycopeptide
Drug class
Vancomycin, a glycopeptide
Class identifiers
UseBacterial infection
ATC codeJ01X
Biological targetinhibit peptidoglycan synthesis
Clinical data
Drugs.comantibiotics.html Drug Classes
Legal status
In Wikidata

Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides. Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin. Vancomycin is used if infection with methicillin-resistant Staphylococcus aureus (MRSA) is suspected.

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Glycopeptide antibiotic

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Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides. Significant...

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Glycopeptide

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of the cysteine residue to an alanine. Carbohydrate chemistry Glycopeptide antibiotic Glycosylation Peptide synthesis Talbot P.; Shur B. D.; Myles D...

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Vancomycin

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Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. It is used intravenously (injection into a vein) as...

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Staphylococcus aureus

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which have become resistant to most β-lactam antibiotics. For this reason, vancomycin, a glycopeptide antibiotic, is commonly used to combat MRSA. Vancomycin...

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Antibiotic

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Lessard IA, Park I, Wright GD (September 1998). "Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms". Antimicrobial Agents and...

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Aminoglycoside

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mechanism of action. (For instance, vancomycin, a glycopeptide antibiotic, and erythromycin, a macrolide antibiotic produced by Saccharopolyspora erythraea, along...

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Teicoplanin

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Teicoplanin is an semisynthetic glycopeptide antibiotic with a spectrum of activity similar to vancomycin. Its mechanism of action is to inhibit bacterial...

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List of antibiotics

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The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly...

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Zeocin

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phleomycin D1, a glycopeptide antibiotic and one of the phleomycins from Streptomyces verticillus belonging to the bleomycin family of antibiotics. It is a broad-spectrum...

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Linezolid

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linezolid to be more effective than glycopeptide antibiotics (such as vancomycin and teicoplanin) and beta-lactam antibiotics in the treatment of skin and soft...

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Penicillin

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the entire depth of the cell wall. This is in contrast to the glycopeptide antibiotics vancomycin and teicoplanin, which are both much larger than the...

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Oritavancin

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under the brand name Orbactiv among others, is a semisynthetic glycopeptide antibiotic medication for the treatment of serious Gram-positive bacterial...

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Chloroeremomycin

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Chloroeremomycin is a member of the glycopeptide family of antibiotics, such as vancomycin. The molecule is a non-ribosomal polypeptide that has been glycosylated...

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Dalbavancin

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improve upon the natural glycopeptides vancomycin and teicoplanin. It is derived from a complex of glycopeptide antibiotics, referred to as A-40926, that...

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Mannopeptimycin glycopeptide

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Mannopeptimycin glycopeptide is a lead antibiotic peptide. Sum, Phaik-Eng; How, David; Torres, Nancy; Petersen, Peter J.; Lenoy, Eileen B.; Weiss, William...

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Dihydroxyphenylglycine

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, Thaker, M. N., Koteva, K., Wright, G. "Glycopeptide antibiotic biosynthesis." The Journal of Antibiotics, 2017, 67, 31-41. Pfeifer, V., Nicholson,...

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Staphylococcus haemolyticus

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suggests that glycopeptides can be supplemented with β-lactams to work synergistically. S. haemolyticus has the highest level of antibiotic resistance among...

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Ristocetin

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Ristocetin is a glycopeptide antibiotic, obtained from Amycolatopsis lurida, previously used to treat staphylococcal infections. It is no longer used...

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Nonribosomal peptide

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peptide antibiotics, cytostatics, and immunosuppressants are in commercial use. Antibiotics Actinomycin Bacitracin Calcium dependent antibiotic Daptomycin...

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Lipid II

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Copsin Human alpha defensins The D-Ala-D-Ala terminus is used by glycopeptide antibiotic vancomycin to inhibit lipid I- and lipid II-consuming peptidoglycan...

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Bleomycin

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Takeuchi T, Okami Y (September 1966). "New antibiotics, bleomycin A and B". The Journal of Antibiotics. 19 (5): 200–9. PMID 5953301. Song N, Liu J,...

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Corbomycin

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Corbomycin is a member of the glycopeptide family of antibiotics that are produced by soil bacteria. Corbomycin blocks autolysins by attaching to the peptidoglycan...

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Bottromycin

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structurally distinct from both vancomycin, a glycopeptide antibiotic, and methicillin, a beta-lactam antibiotic. Bottromycin binds to the A site of the ribosome...

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Chiral analysis

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various chiral selectors including polysaccharides, cyclodextrins, glycopeptide antibiotics, proteins, Pirkle, crown ethers, etc. to achieve analysis of chiral...

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Antibiotic use in livestock

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Antibiotic use in livestock is the use of antibiotics for any purpose in the husbandry of livestock, which includes treatment when ill (therapeutic),...

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Peptidoglycan

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"A review on cell wall synthesis inhibitors with an emphasis on glycopeptide antibiotics". MedChemComm. 8 (3): 516–533. doi:10.1039/c6md00585c. PMC 6072328...

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Avoparcin

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Avoparcin is a glycopeptide antibiotic effective against Gram-positive bacteria. It has been used in agriculture as an additive to livestock feed to promote...

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