Thus, the two substrates of this enzyme are glycolate and acceptor, whereas its two products are glyoxylate and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is glycolate:acceptor 2-oxidoreductase. Other names in common use include glycolate oxidoreductase, glycolic acid dehydrogenase, and glycolate:(acceptor) 2-oxidoreductase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
and 19 Related for: Glycolate dehydrogenase information
In enzymology, a glycolatedehydrogenase (EC 1.1.99.14) is an enzyme that catalyzes the chemical reaction glycolate + acceptor ⇌ {\displaystyle \rightleftharpoons...
Alcohol dehydrogenases (ADH) (EC 1.1.1.1) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between...
altogether. In 2019, they transferred Chlamydomonas reinhardtii glycolatedehydrogenase and Cucurbita maxima malate synthase into the chloroplast of tobacco...
\rightleftharpoons } glycolate + NADH + H+ The 3 substrates of this enzyme are glycolaldehyde, NAD+, and H2O, whereas its 3 products are glycolate, NADH, and H+...
L-malate, catalyzed by malate dehydrogenase, in the citric acid cycle. Malate is also oxidized by succinate dehydrogenase in a slow reaction with the initial...
activity. The ability of GRHPR to reduce glyoxylate to glycolate is found in other glycerate dehydrogenase homologs as well. This is important for the intracellular...
mitochondria. It has also been reported that the pyruvate dehydrogenase complex may play a role in glycolate and glyoxylate metabolism. Glyoxylate is thought to...
glycolaldehyde by alcohol dehydrogenase. Glycolaldehyde then undergoes further oxidation to glycolate, glyoxylate, and oxalate. Glycolate and oxalate are the...
reduction of glyoxylate to glycolate, using the cofactor NADH or NADPH. The systematic name of this enzyme class is glycolate:NAD+ oxidoreductase. Other...
acid, glyoxylic acid and oxalic acid by aldehyde dehydrogenase, lactate dehydrogenase (LDH) and glycolate oxidase in mammalian organisms. The accumulation...
and 2-phosphoglycolate, a 2-carbon molecule that can be converted via glycolate and glyoxalate to glycine. Via the glycine cleavage system and tetrahydrofolate...
Itaconate inhibits isocitrate lyase and thereby the functioning of the glycolate cycle and the growth of cultured and/or phagocytosed Staphylococcus aureus...
Kohler; E. Menotti & L. C. Kuhn (January 1999). "Molecular cloning of mouse glycolate oxidase. High evolutionary conservation and presence of an iron-responsive...
Kerns W, Tomaszewski CA, McMartin KE, Rose SR, Ford MD, Brent J (1998). "Glycolate kinetics and hemodialysis clearance in ethylene glycol poisoning. META...
spectroscopy. Alternatively, lactate dehydrogenase can be used to catalyse the reduction of glyoxylate to glycolate in the presence of nicotinamide adenine...
ISSN 0969-2126. "Pfam entry: FMN-dependent dehydrogenase". Archived from the original on 2007-09-29. Retrieved 2007-01-25. "Glycolate oxidase - Proteopedia, life in...
reduce the efficiency of CO2 fixation and result in the excretion of glycolate. Under these conditions, clumping can be beneficial to cyanobacteria if...
mRNA for breakdown. Lowering HAO1 enzyme levels reduces the oxidation of glycolate to glyoxylate (which is a substrate for oxalate). Lumasiran is administered...
RuBisCO adds oxygen instead of carbon dioxide, to form the unusable product glycolate in a process called photorespiration. To prevent this wasteful process...
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