Glucocerebroside (also called glucosylceramide) is any of the cerebrosides in which the monosaccharide head group is glucose. In Gaucher's disease, the...
that cleaves by hydrolysis the β-glycosidic linkage of the chemical glucocerebroside, an intermediate in glycolipid metabolism that is abundant in cell...
either glucose or galactose; the two major types are therefore called glucocerebrosides (a.k.a. glucosylceramides) and galactocerebrosides (a.k.a. galactosylceramides)...
synthase) is a glucosyltransferase enzyme involved in the production of glucocerebroside. It is classified under EC 2.4.1.80. It is inhibited by miglustat and...
Galactocerebrosides: a type of cerebroseide with galactose as the saccharide moiety Glucocerebrosides: a type of cerebroside with glucose as the saccharide moiety; often...
Juvenile hexosaminidase A deficiency Chronic hexosaminidase A deficiency Glucocerebroside Gaucher disease Type I Type II Type III Sphingomyelinase Lysosomal...
treatment of Gaucher disease Type 1. It is a hydrolytic lysosomal glucocerebroside-specific enzyme, which is a recombinant form of glucocerebrosidase...
is to convert glucocerebroside (also known as glucosylceramide) into ceramide and glucose. When this enzyme doesn't work, glucocerebroside accumulates,...
β-Glucocerebrosidase, an enzyme needed for the metabolisation of glucocerebroside, is misfolded in individuals with Gaucher's disease due to various...
stimulate the enzymatic hydrolysis of 4-methylumbelliferyl-β-glucoside, glucocerebroside, and galactocerebroside. Saposin B was the first to be discovered and...
Kanfer JN, Bradley RM, Shapiro D. Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease. J Clin Invest 1966; 45: 1112–1115...
Klenk did research on phospholipids, glycolipids, cerebrosides, glucocerebrosides, sphingosines, sphingolipids, glycosphingolipids, gangliosides, plasmalogens...
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