Gene Relationships Across Implicated Loci information

Gene Relationships Across Implicated Loci (GRAIL) is a free web application developed by Soumya Raychaudhuri at the Broad Institute with the goal of determining...

categorizes genes by their functional products (proteins or RNA) rather than their specific DNA loci, with regulatory elements classified as gene-associated...

the transcriptome of murine brain tissues revealed over 1300 imprinted gene loci (approximately 10-fold more than previously reported) by RNA-sequencing...

Developmental Loci in Drosophila melanogaster", a TE, inserted between Jheh 2 and Jheh 3, revealed a downgrade in the expression level of both of the genes. Downregulation...

by epigenetic events. Subtle, epigenetic modifications at many genomic loci (gene regulatory networks) alter the shape of the canal in response to environmental...

each autistic individual, mutations in many genes are typically implicated. Mutations in different sets of genes may be involved in different autistic individuals...

targets a V. cholera PICI-like element. The system has 2 CRISPR loci and 9 Cas genes. It seems to be homologous to the I-F system found in Yersinia pestis...

regulatory gene-expression networks. In conclusion, though not much is known about the role and mechanism by which SINEs generate miRNA gene loci it is generally...

Each gene has a unique, fixed location, known as a locus, within the dog genome. Some of the loci associated with canine coat color are: Several loci can...

1990). "Linkage relationships of human arginine vasopressin-neurophysin-II and oxytocin-neurophysin-I to prodynorphin and other loci on chromosome 20"...

related to each other at the gene level. By comparing whole genome sequences, researchers gain insights into genetic relationships between organisms and study...

with allergy genes encoding cytokines, chemokines and other transcription factors occur. For the study of the relationships between loci and cat allergy...

RNA sequences have shown to play a key role in the regulation of gene expression. Gene expression can be controlled through the action of repressor proteins...

these genes may predispose to common obesity. Many candidate genes are highly expressed in the central nervous system. Several additional loci have been...

with LDL-R gene family receptors. Considering its association with lipoprotein levels, APOA5 is implicated in metabolic syndrome. The APOA5 gene also contains...

mitochondrial disease, can also trigger depressive symptoms. Neural circuits implicated in depression include those involved in the generation and regulation...

under-activated in bipolar, and is generally implicated in cognitive functions, while the ventral ACC is hyperactive and implicated in emotional functions. Combined...

dataset was expanded to identify in total 13 candidate loci for the disease, and also implicated calcium signaling as an important factor in the disease...

suppressor is a protein which in humans is encoded by the DCC gene. DCC has long been implicated in colorectal cancer and its previous name was Deleted in...

functional, transcriptional, and epigenetic changes linked to the immune gene loci. The responsiveness of myeloid cells to the Candida albicans infection...

are a number of genes that affect a person's risk of contracting type 2 diabetes. The same applies for obesity, which has several loci in common with the...

phosphatase present, which are determined by a minimum of three gene loci. Each one of these three loci controls a different kind of alkaline phosphatase isozyme...

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence. Nat Genet. 2017 Jul;49(7):1107-1112...

that, in humans, is encoded by the CHD1 gene. CHD1 is a chromatin remodeling protein that is widely conserved across many eukaryotic organisms, from yeast...

very much larger sample sizes would be necessary to identify responsible loci in disorders such as schizophrenia using linkage because of incomplete penetrance...