extracellularly glutamate-gated ion channel activity
NMDA glutamate receptor activity
glutamate-gated calcium ion channel activity
signaling receptor activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
Cellular component
integral component of membrane
postsynaptic membrane
membrane
postsynaptic density
plasma membrane
synapse
cell junction
intracellular anatomical structure
integral component of plasma membrane
NMDA selective glutamate receptor complex
postsynaptic density membrane
glutamatergic synapse
Biological process
protein localization
glutamate receptor signaling pathway
neuromuscular process controlling balance
negative regulation of protein catabolic process
regulation of membrane potential
directional locomotion
ion transport
MAPK cascade
ionotropic glutamate receptor signaling pathway
response to wounding
excitatory postsynaptic potential
calcium-mediated signaling
calcium ion transmembrane import into cytosol
regulation of molecular function
transport
brain development
regulation of synaptic plasticity
long-term potentiation
excitatory chemical synaptic transmission
protein localization to postsynaptic membrane
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
2905
14813
Ensembl
ENSG00000161509
ENSMUSG00000020734
UniProt
Q14957
Q01098
RefSeq (mRNA)
NM_000835 NM_001278553
NM_010350
RefSeq (protein)
NP_000826 NP_001265482
NP_034480
Location (UCSC)
Chr 17: 74.84 – 74.86 Mb
Chr 11: 115.14 – 115.16 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000161509 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000020734 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kalsi G, Whiting P, Bourdelles BL, Callen D, Barnard EA, Gurling H (Apr 1998). "Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels". Genomics. 47 (3): 423–5. doi:10.1006/geno.1997.5132. PMID 9480759.
receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate...
receptor are encoded by GRIN genes: GRIN1 codes for GluN1; GRIN2A, GRIN2B, GRIN2C, and GRIN2D code for GluN2 A to D; GRIN3A and GRIN3B code for GluN3A and...
the four NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). The NR2 subunit acts as the agonist binding site...
of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). Variants of the gene are associated with the protective...
17 at the locus 17q25.1. TMEM104 is located between the genes NAT9 and GRIN2C. There are 7 main transcription variants: isoform 1, isoform 2, variant...
of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2D has been shown to interact with Interleukin...