GRB2-related adapter protein 2 also known as GRB2-related adaptor downstream of Shc (GADS) is a 37 kDa protein that in humans is encoded by the GRAP2 gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000100351 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000042351 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Qiu M, Hua S, Agrawal M, Li G, Cai J, Chan E, Zhou H, Luo Y, Liu M (Dec 1998). "Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1". Biochemical and Biophysical Research Communications. 253 (2): 443–7. doi:10.1006/bbrc.1998.9795. PMID 9878555.
^Asada H, Ishii N, Sasaki Y, Endo K, Kasai H, Tanaka N, Takeshita T, Tsuchiya S, Konno T, Sugamura K (May 1999). "Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT". The Journal of Experimental Medicine. 189 (9): 1383–90. doi:10.1084/jem.189.9.1383. PMC 2193052. PMID 10224278.
^"Entrez Gene: GRAP2 GRB2-related adaptor protein 2".
downstream of Shc (GADS) is a 37 kDa protein that in humans is encoded by the GRAP2 gene. This gene encodes a member of the GRB2/Sem5/Drk family. This member...
has been shown to interact with: B-cell linker, CRK, CRKL, Drebrin-like, GRAP2, Grb2, Linker of activated T cells, and NCK1. ENSG00000104814 GRCh38: Ensembl...
C-terminal SH3 domains of adaptor proteins like Grb2 and Mona (a.k.a. Gads, Grap2, Grf40, GrpL etc.). Other SH3 binding motifs have emerged and are still...
on the C-terminius side are outside of the cell. The paralogous domain Grap2 and cyclin-D-interacting (pfam13324) spans from 81-151 and is highly conserved...
which prevents CD28 homodimerization. CD28 has been shown to interact with: GRAP2, Grb2, and PIK3R1. List of human clusters of differentiation GRCh38: Ensembl...
gene. This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling...
been shown to interact with RNF11, Signal transducing adaptor molecule and GRAP2. GRCm38: Ensembl release 89: ENSMUSG00000006906 – Ensembl, May 2017 "Human...
Look up gads in Wiktionary, the free dictionary. GADS may refer to: GRAP2, GRB2-related adapter protein 2 involved in leukocyte-specific protein-tyrosine...
of the amino acid sequence. The PDB file 1H3H depicts the SH3 domain of GRAP2 in complex with an RSTK-containing peptide representing residues 226–235...
Tabassam F, Ma W, Qiu M, Hua S, Liu M (July 2000). "GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F-mediated transcriptional...
The Linker for Activation of T cells has been shown to interact with: GRAP2, GRAP, Grb2, ITK, MAP4K1 PIK3R1, PLCG1, SHB, VAV1, and ZAP-70. GRCh38: Ensembl...
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