positive regulation of cytosolic calcium ion concentration
positive regulation of Rho protein signal transduction
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
chemokine-mediated signaling pathway
negative regulation of voltage-gated calcium channel activity
negative regulation of neuronal action potential
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
2859
64095
Ensembl
ENSG00000178623
ENSMUSG00000026271
UniProt
Q9HC97
Q9ES90
RefSeq (mRNA)
NM_005301 NM_001195381 NM_001195382 NM_001394730
NM_001104529 NM_001271766 NM_022320
RefSeq (protein)
NP_001182310 NP_001182311 NP_005292
NP_001097999 NP_001258695 NP_071715
Location (UCSC)
Chr 2: 240.61 – 240.63 Mb
Chr 1: 92.88 – 92.91 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene.[5] Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.
^ abcGRCh38: Ensembl release 89: ENSG00000178623 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000026271 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^O'Dowd BF, Nguyen T, Marchese A, Cheng R, Lynch KR, Heng HH, Kolakowski LF, George SR (1998). "Discovery of three novel G-protein-coupled receptor genes". Genomics. 47 (2): 310–3. doi:10.1006/geno.1998.5095. PMID 9479505.
35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune...
Pamoic acid has agonist activity for the orphan G protein-coupled receptor GPR35 by which it activates ERK and beta-arrestin2, and causes antinociceptive...
protein-coupled receptor (GPCR). The GPCR GPR35 was thought to be a receptor of CXCL17. Subsequent research has suggested that GPR35 is not a receptor for CXCL17....
also been shown to activate the orphan G-protein coupled receptor known as GPR35, both in rats and humans, and to inhibit the mitochondrial pyruvate carrier...
and bufrolin as the first high and equipotent agonists of human and rat GPR35". Molecular Pharmacology. 85 (1): 91–104. doi:10.1124/mol.113.089482. ISSN 0026-895X...
receptor currents. As a ligand for the orphan G protein-coupled receptor GPR35. As an agonist for the G protein-coupled receptor HCAR3. High levels of...
are also intermediates in the synthesis of phosphatidic acids. Autotaxin GPR35 Phosphatidic acid Sphingosine-1-phosphate Gintonin van Corven, Emile J.;...
syndrome has been defined as a 3 megabase region that contains the genes GPR35, GPC1 and STK25. Almost all deletions are found to be terminal deletions...