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GENCODE information


GENCODE
Content
DescriptionEncyclopædia of genes and gene variants
Data types
captured
All gene features in Human & mouse genome
Contact
Research centerWellcome Trust Sanger Institute
AuthorsHarrow J, et al [1]
Primary citationPMID 22955987
Release dateSeptember 2012 (September 2012)
Access
WebsiteWebsite Gencode
Tools
WebUCSC Genome Browser: http://genome.cse.ucsc.edu/encode/
Miscellaneous
LicenseOpen Access
Data release
frequency
Human - Quarterly
Mouse - Half yearly
VersionHuman - Release 37 (February 2021)
Mouse - Release M26 (February 2021)

GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project.

The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. 1% of Human genome).[2] Given the initial success of the project, GENCODE now aims to build an “Encyclopedia of genes and genes variants”.[2]

The result will be a set of annotations including all protein-coding loci with alternatively transcribed variants,[3] non-coding loci[4] with transcript evidence, and pseudogenes.[5]

  1. ^ Harrow J, Frankish A, Gonzalez JM, Tapanari E, Diekhans M, Kokocinski F, et al. (September 2012). "GENCODE: the reference human genome annotation for The ENCODE Project" (PDF). Genome Research. 22 (9): 1760–74. doi:10.1101/gr.135350.111. PMC 3431492. PMID 22955987.
  2. ^ a b Harrow J, Denoeud F, Frankish A, Reymond A, Chen CK, Chrast J, et al. (2006). "GENCODE: producing a reference annotation for ENCODE". Genome Biology. 7 (Suppl 1): S4.1–9. doi:10.1186/gb-2006-7-s1-s4. PMC 1810553. PMID 16925838.
  3. ^ Frankish A, Mudge JM, Thomas M, Harrow J (2012). "The importance of identifying alternative splicing in vertebrate genome annotation". Database. 2012: bas014. doi:10.1093/database/bas014. PMC 3308168. PMID 22434846.
  4. ^ Derrien T, Johnson R, Bussotti G, Tanzer A, Djebali S, Tilgner H, et al. (September 2012). "The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression". Genome Research. 22 (9): 1775–89. doi:10.1101/gr.132159.111. PMC 3431493. PMID 22955988.
  5. ^ Pei B, Sisu C, Frankish A, Howald C, Habegger L, Mu XJ, et al. (September 2012). "The GENCODE pseudogene resource". Genome Biology. 13 (9): R51. doi:10.1186/gb-2012-13-9-r51. PMC 3491395. PMID 22951037.

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GENCODE

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GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project. The GENCODE consortium was initially...

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Markup language

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device. In the 1970s, Tunnicliffe led the development of a standard called GenCode for the publishing industry and later was the first chairman of the International...

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Exon

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Hubbard, TJ; Notredame, C; Harrow, J; Guigó, R (September 2012). "The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure...

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Human brain

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1186/s13073-017-0441-1. PMC 5448149. PMID 28558813. Harrow, J.; et al. (September 2012). "GENCODE: the reference human genome annotation for The ENCODE Project". Genome...

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Cdist

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code re-use easy. Gencode Scripts: The gencode-remote script is the main way to actually update the configuration of target nodes. gencode-remote runs on...

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Bayswater Power Station

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au/show/unit/YYYYMMDD/YYYYMMDD/?k1=GENCODE[permanent dead link] where YYYYMMDD are start and end dates and GENCODE is one of BW01, BW02, BW03, or BW04...

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Wellcome Sanger Institute

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effort to describe different cancer tumour types. It is also part of the GENCODE and ENCODE research programmes to create an encyclopaedia of DNA elements...

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Tim Hubbard

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Rossier, C; Ucla, C; Hubbard, T; Antonarakis, S. E.; Guigo, R (2006). "GENCODE: Producing a reference annotation for ENCODE". Genome Biology. 7 (Suppl...

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Pseudogene

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Frankish A, Howald C, Habegger L, Mu XJ, et al. (September 2012). "The GENCODE pseudogene resource". Genome Biology. 13 (9): R51. doi:10.1186/gb-2012-13-9-r51...

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Gene

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genes however that estimate has fallen to about 19,000 with the ongoing GENCODE annotation project. The number of noncoding genes is not known with certainty...

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Manolis Kellis

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comprehensive map of conserved elements in the human genome, the ENCODE, GENCODE, and modENCODE projects to characterize the genes, non-coding elements...

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UCSC Genome Browser

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pre-selected sets of genes to look for correlations between known sets of genes. GENCODE v24, Geneid Genes, Pfam in UCSC Gene Phenotype and Literature Databases...

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Human genome

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Sisu C, Frankish A, Howald C, Habegger L, Mu XJ, et al. (2012). "The GENCODE pseudogene resource". Genome Biology. 13 (9): R51. doi:10.1186/gb-2012-13-9-r51...

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DIRAS1

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PMC 8534260. PMID 34680261. "Human Gene DIRAS1 (ENST00000323469.5) from GENCODE V44". "Di-Ras, a Distinct Subgroup of Ras Family GTPases with Unique Biochemical...

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Udo Ulfkotte

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Fight for Ratios and Editions]. Bertelsmann. 2001. ISBN 978-3570001998. Gencode J: Roman [Gene Code J.]. Eichborn. 2001. ISBN 978-3821808604. Marktplatz...

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DNA annotation

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annotation: Encyclopedia of DNA elements (ENCODE) Entrez Gene Ensembl FlyBase GENCODE Gene Ontology Consortium GeneRIF Mouse Genome Informatics RefSeq Uniprot...

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RefSeq

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the differences in transcripts annotation between RefSeq and Ensembl/GENCODE annotation systems are reduced. A MANE Select transcripts set are created...

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ENCODE

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regions and the distance and orientation preferences between motif sites. GENCODE SIMAP Functional genomics Human Genome Project 1000 Genomes Project International...

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Global Biodata Coalition

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Center) EcoCyc Ensembl Europe PMC European Nucleotide Archive (ENA) FlyBase GENCODE Gene Ontology (GO) Global Biodiversity Information Facility (GBIF) Genome...

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Consensus CDS Project

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section of CCDS sequence data. The CCDS dataset is an integral part of the GENCODE gene annotation project and it is used as a standard for high-quality coding...

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Small RNA sequencing

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transcript annotations from different databases (Mirbase, GtRNAdb and Gencode). Small RNA sequencing can be useful for: studying the expression profile...

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Astrotactin

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protein is generated from Chromosome 1: 176,861,067-177,164,712 and the Gencode Gene: ENSG00000152092.16 with a base pair size of 303,646 and total Exon...

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ANNOVAR

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of the data sources for each annotation type: UCSC/Ensembl genes hg38 GENCODE/CCDS ENCODE Custom-made databases conforming to GFF3 (Generic Feature Format...

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PRR29

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NCBI". www.ncbi.nlm.nih.gov. "Human Gene PRR29 (ENST00000425164.7) from GENCODE V38". genome.ucsc.edu. "NCBI Aceview". "PRR29 proline rich 29 [Homo sapiens...

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UC Santa Cruz Genomics Institute

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played significant roles in large-scale consortium sequencing projects like GENCODE, the Vertebrate Genome Project, Pan-Cancer Initiative, Human Cell Atlas...

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