GABRR3 information

GABRR3
Identifiers
Aliases	GABRR3, gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene), gamma-aminobutyric acid type A receptor subunit rho3 (gene/pseudogene), gamma-aminobutyric acid type A receptor subunit rho3
External IDs	MGI: 3588203; HomoloGene: 26716; GeneCards: GABRR3; OMA:GABRR3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	98,035,315 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	59,284,867 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; islet of Langerhans; ; liver; ; right lobe of liver; ; spleen; ; nucleus accumbens;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; neural layer of retina; ; zygote; ; embryo; ; vasculature; ; vasculature of organ; ; spinal cord; ; temporal lobe; ; amygdala;
	More reference expression data
	n/a
Gene ontology
Molecular function	chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity; ion channel activity; transmembrane signaling receptor activity; protein domain specific binding;
Cellular component	membrane; integral component of membrane; cell junction; GABA-A receptor complex; plasma membrane; postsynaptic membrane; synapse; chloride channel complex; cellular component; integral component of plasma membrane; neuron projection;
Biological process	gamma-aminobutyric acid signaling pathway; chloride transport; chloride transmembrane transport; ion transport; chemical synaptic transmission; ion transmembrane transport; signal transduction; regulation of membrane potential; nervous system process;
	Sources:Amigo / QuickGO
Orthologs
	200959
	328699
	ENSG00000183185
	ENSMUSG00000074991
	A8MPY1
	B2RXA8
	NM_001105580
	NM_001081190
	NP_001099050
	NP_001074659
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit rho-3 is a protein that in humans is encoded by the GABRR3 gene.^[5] The protein encoded by this gene is a subunit of the GABA_A-ρ receptor.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183185 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000074991 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (October 1999). "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3". Biochim. Biophys. Acta. 1447 (2–3): 307–312. doi:10.1016/S0167-4781(99)00167-0. PMID 10542332.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183185 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000074991 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10542332-5] Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (October 1999). "Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3". Biochim. Biophys. Acta. 1447 (2–3): 307–312. doi:10.1016/S0167-4781(99)00167-0. PMID 10542332.

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