Crystal structure of the cysteine-rich domain of mouse frizzled 8 (mfz8)[1]
Identifiers
Symbol
Frizzled
Pfam
PF01534
Pfam clan
GPCR_A
InterPro
IPR000539
PROSITE
PDOC50038
TCDB
9.A.14
OPM superfamily
6
OPM protein
4jkv
CDD
cd13951
Available protein structures:
Pfam
structures / ECOD
PDB
RCSB PDB; PDBe; PDBj
PDBsum
structure summary
Frizzled is a family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways.[2] When activated, Frizzled leads to activation of Dishevelled in the cytosol.
^PDB: 1IJY; Dann CE, Hsieh JC, Rattner A, Sharma D, Nathans J, Leahy DJ (July 2001). "Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains". Nature. 412 (6842): 86–90. Bibcode:2001Natur.412...86D. doi:10.1038/35083601. PMID 11452312. S2CID 4303237.
^Malbon CC (2004). "Frizzleds: new members of the superfamily of G-protein-coupled receptors". Front. Biosci. 9 (1–3): 1048–58. doi:10.2741/1308. PMID 14977528.
other signaling pathways. When activated, Frizzled leads to activation of Dishevelled in the cytosol. Frizzled proteins and the genes that encode them have...
Frizzle Fry is the debut studio album by American rock band Primus. It was released on February 7, 1990, by Caroline Records. Produced by the band and...
The Magic School Bus To fry (food) Frizzle Fry, an album by Primus Frizzle Sizzle, a Dutch musical group Frizzled, a family of proteins This disambiguation...
Secreted frizzled-related protein 4 is a protein that in humans is encoded by the SFRP4 gene. Secreted frizzled-related protein 4 (SFRP4) is a member of...
Albuca spiralis, commonly called the corkscrew albuca or frizzle sizzle, is a species of flowering plant in the family Asparagaceae, that is native to...
focuses on the antics of a fictional elementary school teacher, Ms. Valerie Frizzle, and her class (with Carlos, Keesha, Phoebe, Arnold, Tim, etc.) who board...
Frizzle chicken may refer to: Frizzle (chicken plumage), a curled-feather type of chicken plumage common to certain breeds of domestic chicken Frizzle...
Frizzle Sizzle were a Dutch teenage girl group of the 1980s. Their biggest hit was "Alles Heeft Een Ritme", which they performed at Eurovision in Norway...
or bangs remained fashionable throughout the decade, usually curled or frizzled over the forehead, often called "Josephine Curls." Bonnets resembled hats...
Frizzled (Fz), Flamingo (Fmi), Strabismus (Stbm)/Van-gogh (Vang), Prickle (Pk), Dishevelled (Dsh), Diego (Dgo), and trimeric G protein Gαo. Frizzled (Fz)...
to Scholastic's The Magic School Bus, the flagship Valerie Frizzle (now Professor Frizzle) gets her Ph.D and retires from teaching at Walkerville Elementary...
the royal coat of arms. In 1828 the Duty Ace of Spades (known as "Old Frizzle") was printed to indicate a reduced duty of a shilling had been paid. One...
but can be a lunch or dinner dish too. Eggs frizzle – scrambled egg dish made with chipped beef "frizzled" in butter before eggs are added to the pan...
Secreted frizzled-related protein 2 is a protein that in humans is encoded by the SFRP2 gene. This gene encodes a member of the SFRP family that contains...
Global Information