Fenoprofen information

Fenoprofen
Clinical data
Trade names	Nalfon
AHFS/Drugs.com	Monograph
MedlinePlus	a681026
Pregnancy; category	C;
Routes of; administration	By mouth
ATC code	M01AE04 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only); US: WARNINGRx-only;
Pharmacokinetic data
Metabolism	Major urinary metabolites are fenoprofen glucuronide and 4′-hydroxyfenoprofen glucuronide.
Elimination half-life	3 hours
Excretion	Renal (~90%)
Identifiers
	IUPAC name 2-(3-phenoxyphenyl)propanoic acid;
CAS Number	29679-58-1 ;
PubChem CID	3342;
IUPHAR/BPS	4820;
DrugBank	DB00573 ;
ChemSpider	3225 ;
UNII	RA33EAC7KY;
KEGG	D02350 ;
ChEBI	CHEBI:5004 ;
ChEMBL	ChEMBL1297 ;
CompTox Dashboard (EPA)	DTXSID9023045 ;
ECHA InfoCard	100.046.213 100.045.231, 100.046.213
Chemical and physical data
Formula	C15H14O3
Molar mass	242.274 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)C(c2cc(Oc1ccccc1)ccc2)C;
	InChI InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17) ; Key:RDJGLLICXDHJDY-UHFFFAOYSA-N ;
	(verify)

Fenoprofen, sold under the brand name Nalfon among others, is a nonsteroidal anti-inflammatory drug (NSAID). Fenoprofen calcium is used for symptomatic relief for rheumatoid arthritis, osteoarthritis, and mild to moderate pain. It has also been used to treat postoperative pain.^[2] It is available as a generic medication.^[3]^[4]

^ "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^ Traa MX, Derry S, Moore RA (February 2011). "Single dose oral fenoprofen for acute postoperative pain in adults". The Cochrane Database of Systematic Reviews. 2011 (2): CD007556. doi:10.1002/14651858.CD007556.pub2. PMC 4171001. PMID 21328296.
^ "2022 First Generic Drug Approvals". U.S. Food and Drug Administration (FDA). 3 March 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.
^ "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.

[FDA-AllBoxedWarnings-1] "FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.

[Traa_2011-2] Traa MX, Derry S, Moore RA (February 2011). "Single dose oral fenoprofen for acute postoperative pain in adults". The Cochrane Database of Systematic Reviews. 2011 (2): CD007556. doi:10.1002/14651858.CD007556.pub2. PMC 4171001. PMID 21328296.

[3] "2022 First Generic Drug Approvals". U.S. Food and Drug Administration (FDA). 3 March 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.

[4] "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.

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