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Fate mapping information


Example of a fate map

Fate mapping is a method used in developmental biology to study the embryonic origin of various adult tissues and structures. The "fate" of each cell or group of cells is mapped onto the embryo, showing which parts of the embryo will develop into which tissue. When carried out at single-cell resolution, this process is called cell lineage tracing. It is also used to trace the development of tumors. Fate mapping and cell lineage are similar methods for tracing the history of cells.

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Fate mapping

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Fate mapping is a method used in developmental biology to study the embryonic origin of various adult tissues and structures. The "fate" of each cell...

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Cell lineage

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complicated organisms to be studied. Perhaps the most popular method of cell fate mapping in the genetic era is through site-specific recombination mediated by...

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Gene mapping

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chromosome fine structure Fate mapping G banding Genetic fingerprinting Genome project Human Genome Project Optical mapping Quantitative trait locus Sulston...

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Floor plate

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as Slit/Robo(1-3). In the central nervous system (CNS), overall cell fate mapping is typically directed by the sonic hedgehog (Shh) morphogen signaling...

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Walter Vogt

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was the first scientist to use vital dye to do fate mapping. In 1929, he used vital dyes to construct fate maps of amphibian embryos. www.ijdb.ehu...

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Endoderm

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Kikuchi, Yutaka (August 2005). "Endoderm development in vertebrates: fate mapping, induction and regional specification". Development, Growth and Differentiation...

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Drosophila melanogaster

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others, Benzer and colleagues used sexual mosaics to develop a novel fate mapping technique. This technique made it possible to assign a particular characteristic...

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DiI

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used for scientific staining purposes such as single molecule imaging, fate mapping, electrode marking and neuronal tracing (as DiI is retained in the lipid...

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Cell fate determination

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have made possible the mapping of the cell lineage of Caenorhabditis elegans including its embryo. This technique of fate mapping is used to study cells...

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Olfactory epithelium

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cells, whose contributions have been identified more recently through fate mapping studies. The embryonic olfactory epithelium consists of fewer cell types...

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Imaginal disc

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Pupal and adult tissues form from imaginal cells. Clonal analysis and fate mapping of single, identified cells show that tracheal system remodeling at metamorphosis...

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Cephalopod

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by Adolf Naef in 1928, has increasingly been favoured; for example, fate mapping of limb buds in the chambered nautilus indicates that limb buds originate...

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Gastrulation

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in the development between mice and humans. Blastocyst Deuterostome Fate mapping Primitive node Invagination Neurulation Protostome Vegetal rotation Urry...

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T helper cell

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Duarte JH, Veldhoen M, Hornsby E, Li Y, Cua DJ, et al. (March 2011). "Fate mapping of IL-17-producing T cells in inflammatory responses". Nature Immunology...

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Neurulation

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Bookshelf Shimokita, E; Takahashi, Y (April 2011). "Secondary neurulation: Fate-mapping and gene manipulation of the neural tube in tailbud". Development, Growth...

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Original antigenic sin

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Schiepers, Ariën; van ’t Wout, Marije; et al. (6 September 2022). "Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated...

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Cerebral organoid

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studied using cerebral organoids. Clonal lineage tracing is part of fate mapping, where the lineage of differentiated tissues is traced to the pluripotent...

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Burkhard Becher

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tissue specific neuroinflammation. In 2019, he explored the role of fate-mapping of GM-CSF expression in terms of identifying a discrete subset of inflammation-driving...

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Endogenous cardiac stem cell

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myocytes in the adult myocardium. Indeed, recent evidence from a genetic fate-mapping study established that stem cells replenish adult mammalian cardiomyocytes...

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Miriam Merad

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PMID 12415265. Ginhoux, F; Greter, M; Leboeuf, M; Nandi, S; Merad, M (2010). "Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages"...

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Ctenophora

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S2CID 17105070. Martindale, M. Q.; Henry, J. Q. (October 1999). "Intracellular Fate Mapping in a Basal Metazoan, the Ctenophore Mnemiopsis leidyi, Reveals the Origins...

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Somitogenesis

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each other. Regarding the paraxial mesoderm from which somites form, fate mapping experiments at the blastula stage show pre-somitic mesoderm progenitors...

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Alfred Sturtevant

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behavior, the first reparable gene defect, the principle underlying fate mapping, the phenomena of unequal crossing-over, and position effect. His main...

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Neurula

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Shimokita, Eisuke; Takahashi, Yoshiko (April 2011). "Secondary neurulation: Fate-mapping and gene manipulation of the neural tube in tail bud". Development, Growth...

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GESTALT

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determined by DNA or RNA sequencing to link it to a developmental lineage. Fate mapping is the process of identifying the embryonic origins of adult tissues...

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Rhombomere

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Pasqualetti M, Díaz C, Renaud JS, Rijli FM, Glover JC (September 2007). "Fate-mapping the mammalian hindbrain: segmental origins of vestibular projection neurons...

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