Protein-coding gene in humans
FRMPD4 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4WND, 4WNE, 4WNF, 4WNG
Identifiers Aliases FRMPD4 , PDZD10, PDZK10, FERM and PDZ domain containing 4, MRX104External IDs OMIM: 300838; MGI: 3042378; HomoloGene: 45843; GeneCards: FRMPD4; OMA:FRMPD4 - orthologs Gene location (Human) Chr. X chromosome (human)[1] Band Xp22.2 Start 12,138,466 bp[1] End 12,724,523 bp[1]
Gene location (Mouse) Chr. X chromosome (mouse)[2] Band X|X F5 Start 166,254,305 bp[2] End 167,360,227 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus endothelial cell Brodmann area 23 Brodmann area 46 orbitofrontal cortex superior frontal gyrus postcentral gyrus primary visual cortex entorhinal cortex prefrontal cortex
Top expressed in dentate gyrus of hippocampal formation granule cell hippocampus proper primary visual cortex superior frontal gyrus cerebellum cerebellar cortex striatum of neuraxis vasculature vasculature of organ olfactory bulb
More reference expression data
BioGPS
Gene ontology Molecular function
phosphatidylinositol-4,5-bisphosphate binding
protein binding
lipid binding
Cellular component
dendritic spine
cell projection
cytoskeleton
protein-containing complex
postsynaptic density
glutamatergic synapse
Biological process
positive regulation of synapse structural plasticity
postsynaptic actin cytoskeleton organization
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001033330 NM_001290427 NM_001290428 NM_001359072 NM_001368936 NM_001369234
RefSeq (protein) NP_055543 NP_001355324 NP_001355325 NP_001355326 NP_001355327 NP_001355328 NP_001355329 NP_001355330 NP_001355331
NP_001028502 NP_001277356 NP_001277357 NP_001346001 NP_001355865 NP_001356163
Location (UCSC) Chr X: 12.14 – 12.72 Mb Chr X: 166.25 – 167.36 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
FERM and PDZ domain containing 4 is a protein that in humans is encoded by the FRMPD4 gene.
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000169933 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000049176 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: FERM and PDZ domain containing 4". Retrieved 2016-10-01 .