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FAN1 information


FAN1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFAN1, KIAA1018, KMIN, MTMR15, hFANCD2/FANCI-associated nuclease 1, FANCD2 and FANCI associated nuclease 1
External IDsOMIM: 613534; MGI: 3045266; HomoloGene: 45598; GeneCards: FAN1; OMA:FAN1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001146094
NM_001146095
NM_001146096
NM_014967

NM_177893

RefSeq (protein)

NP_001139566
NP_001139567
NP_001139568
NP_055782

NP_808561

Location (UCSC)Chr 15: 30.89 – 30.94 MbChr 7: 64 – 64.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

FANCD2/FANCI-associated nuclease 1 (KIAA1018) is an enzyme that in humans is encoded by the FAN1 gene. It is a structure dependent endonuclease. It is thought to play an important role in the Fanconi Anemia (FA) pathway.[5]

  1. ^ a b c ENSG00000198690 GRCh38: Ensembl release 89: ENSG00000276787, ENSG00000198690 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000033458 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FANCD2/FANCI-associated nuclease 1".

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