Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.
^"Aromasin - Summary of Product Characteristics (SmPC)". (emc). 16 May 2022. Retrieved 29 November 2022.
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens...
exemestane. Exemestane went through clinical trials in the 1990s and received FDA approval in 1999, marketed as Aromasin. Indication for exemestane is...
approved to treat breast cancer: Irreversible steroidal inhibitors, such as exemestane (Aromasin), forms a permanent and deactivating bond with the aromatase...
by virtue of its similarity to the DNA repair protein's target lesion. Exemestane, a drug used in the treatment of breast cancer, is an inhibitor of the...
(everolimus) to exemestane therapy against advanced breast cancer can significantly improve progression-free survival compared with exemestane therapy alone...
positive. Inhibitors that are in current clinical use include anastrozole, exemestane, and letrozole. Aromatase inhibitors are also beginning to be prescribed...
or triptorelin) and aromatase inhibitors (anastrozole, letrozole, or exemestane) slightly improves survival, but has more severe side effects. Side effects...
decrease serum concentrations of the aromatase inhibitors anastrozole and exemestane by 90% and 50%, respectively, which could reduce their effectiveness....
1776 u) may refer to: Dimestrol, or dianisylhexene Ethinylestradiol (EE) Exemestane This set index page lists chemical structure articles associated with...
vary tremendously worldwide, as was documented by the 2004 'Intergroup Exemestane Study', an analysis of surgical techniques used in an international trial...
Argus Leader. Gannett. Retrieved 26 August 2015.[permanent dead link] "Exemestane with or without Entinostat in Treating Patients with Recurrent Hormone...
Global Information
(what is this?) (verify)