Charles Ernest Overton (1865–1933) was a British and Swedish physiologist and biologist, now regarded as a pioneer of the theory of the cell membrane.[1]
In the last years of the 19th century Overton did experimental work, allowing the distinction to be drawn between the cell wall of plants and their cytoplasmic membrane.[2] He studied the permeability of a range of biological materials to around 500 chemical compounds.[3]
In 1900, Overton proposed a biomembrane model "Overton Biomembrane Model" which stated that biomembranes are made up of lipids. He gave this statement on the basis of observation of transport of lipid soluble substances across the biomembranes.
He came to Lund University in Sweden as a professor, and married Louise Petrén-Overton, the first woman in Sweden with a doctorate in mathematics; they had four children.[4][5]
^Membrane Permeability: 100 Years Since Ernest Overton: 100 Years Since Ernest Overton. Academic Press. 21 May 1999. p. 1. ISBN 978-0-08-058519-2.
^Henry Harris (2000). The Birth of the Cell. Yale University Press. pp. 152–. ISBN 978-0-300-08295-1.
^Randy O. Wayne (15 September 2009). Plant Cell Biology: From Astronomy to Zoology. Academic Press. p. 18. ISBN 978-0-08-092127-3.
^Larsson, Lisbeth, "Hedvig Louise Beata Petrén-Overton", Svenskt kvinnobiografiskt lexikon [Biographical Dictionary of Swedish Women] (in Swedish), retrieved 13 January 2019
^Haikola, Lars (2006), "Louise Petrén-Overton, my grandmother", Archives of ALGA, 3: 8–9
Charles ErnestOverton (1865–1933) was a British and Swedish physiologist and biologist, now regarded as a pioneer of the theory of the cell membrane....
most cases. This is the Meyer-Overton hypothesis put forward in 1899–1901 by Hans Horst Meyer and Charles ErnestOverton. MAC is inversely related to potency...
permeability that cell membranes gained more recognition. In 1895, ErnestOverton proposed that cell membranes were made of lipids. The lipid bilayer...
extended by evidence from the study of anesthetics. Hans Horst Meyer and ErnestOverton independently noticed that the chemicals which act as general anesthetics...
such as, cilia and flagella, dendritic spines, and yeast buds. 1895 – ErnestOverton hypothesized that cell membranes are made out of lipids. 1925 – Evert...
The results were inconclusive. In 1899 and 1901 Hans Horst Meyer and ErnestOverton respectively made the major discovery that the general anaesthetic action...
years later a similar theory was published independently by Charles ErnestOverton. Meyer compared the potency of many agents, defined as the reciprocal...
similar theory was published independently by Charles ErnestOverton. What became known as the Meyer-Overton hypothesis may be illustrated by a graph comparing...
passes a small fortune into Overton's keeping, with the agreement that once Ernest is twenty-eight, he can receive it. As Ernest develops into a young man...
later, Charles ErnestOverton (1865–1933) independently came to the same conclusion. This correlation became known as the Meyer-Overton hypothesis. It...
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