Global Information Lookup Global Information

Ergocryptine information


Not to be confused with Ergocristine.
α-Ergocryptine
Identifiers
CAS Number
  • 511-09-1 checkY
PubChem CID
  • 134551
IUPHAR/BPS
  • 271
ChemSpider
  • 118591 ☒N
UNII
  • 6WFB60157B
ChEMBL
  • ChEMBL1403281 ☒N
CompTox Dashboard (EPA)
  • DTXSID70893244 Edit this at Wikidata
ECHA InfoCard100.007.384 Edit this at Wikidata
Chemical and physical data
FormulaC32H41N5O5
Molar mass575.710 g·mol−1
3D model (JSmol)
  • Interactive image
SMILES
  • O=C3N1CCC[C@H]1[C@]2(O)O[C@](C(=O)N2[C@H]3CC(C)C)(NC(=O)[C@@H]7/C=C6/c4cccc5c4c(c[nH]5)C[C@H]6N(C)C7)C(C)C
InChI
  • InChI=1S/C32H41N5O5/c1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)4)34-28(38)20-13-22-21-8-6-9-23-27(21)19(15-33-23)14-24(22)35(5)16-20/h6,8-9,13,15,17-18,20,24-26,33,41H,7,10-12,14,16H2,1-5H3,(H,34,38)/t20-,24-,25+,26+,31-,32+/m1/s1 ☒N
  • Key:YDOTUXAWKBPQJW-NSLWYYNWSA-N ☒N
 ☒NcheckY (what is this?)  (verify)
β-Ergocryptine
Names
Other names
(5'αS)-sec-Butyl-12'-hydroxy-2'-isopropylergotaman-3',6',18-trione
Identifiers
CAS Number
  • 20315-46-2 checkY
3D model (JSmol)
  • Interactive image
ECHA InfoCard 100.007.384 Edit this at Wikidata
EC Number
  • 243-728-6
IUPHAR/BPS
  • 988
PubChem CID
  • 161309
UNII
  • 6ZAY944SI4 checkY
CompTox Dashboard (EPA)
  • DTXSID70893244 Edit this at Wikidata
InChI
  • InChI=1S/C32H41N5O5/c1-6-18(4)27-29(39)36-12-8-11-25(36)32(41)37(27)30(40)31(42-32,17(2)3)34-28(38)20-13-22-21-9-7-10-23-26(21)19(15-33-23)14-24(22)35(5)16-20/h7,9-10,13,15,17-18,20,24-25,27,33,41H,6,8,11-12,14,16H2,1-5H3,(H,34,38)/t18-,20+,24+,25-,27+,31+,32-/m0/s1
    Key: YYWXOXLDOMRDHW-SGVWFJRMSA-N
SMILES
  • CC[C@H](C)[C@@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=CNC7=CC=CC(=C67)C5=C4)C)O
Properties
Chemical formula
 C32H41N5O5
Molar mass 575.710 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Ergocryptine is an ergopeptine and one of the ergoline alkaloids. It is isolated from ergot or fermentation broth and it serves as starting material for the production of bromocriptine.[1] Two isomers of ergocryptine exist, α-ergocryptine and β-ergocryptine.[2] The beta differs from the alpha form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid leucine is replaced by isoleucine. β-Ergocryptine was first identified in 1967 by Albert Hofmann.[3] Ergot from different sources have different ratios of the two isomers.[4]

  1. ^ Kren V, Cvak L (1999). Ergot: the genus Claviceps. Amsterdam: Harwood Academic Publishers. pp. 399–401. ISBN 9789057023750.
  2. ^ Yates SG, Plattner RD, Garner GB (1985). "Detection of ergopeptine alkaloids in endophyte-infected, toxic Ky-31 tall fescue by mass spectrometry/mass spectrometry" (PDF). Journal of Agricultural and Food Chemistry. 33 (4): 719–722. doi:10.1021/jf00064a038.[permanent dead link]
  3. ^ Schlientz W, Brunner R, Rüegger A, Berde B, Stürmer E, Hofman A (December 1967). "Beta-ergokryptine, a new alkaloid of the ergotoxine group". Experientia. 23 (12): 991–992. doi:10.1007/BF02136400. PMID 4965668. S2CID 2328419.
  4. ^ Schlientz W, Brunner R, Ruegger A, Berde B, Stuermer E, Hofmann A (1968). "Ergot alkaloids. LXVII. β-Ergocryptine, a new alkaloid of the ergotoxin series". Pharmaceutica Acta Helvetiae. 43 (8): 497–509.

and 10 Related for: Ergocryptine information

Request time (Page generated in 0.5323 seconds.)

Ergocryptine

Last Update:

the production of bromocriptine. Two isomers of ergocryptine exist, α-ergocryptine and β-ergocryptine. The beta differs from the alpha form only in the...

Word Count : 987

Bromocriptine

Last Update:

a natural ergot alkaloid, ergocryptine (a derivative of lysergic acid), which is synthesized by bromination of ergocryptine using N-bromosuccinimide....

Word Count : 1943

Ergoline

Last Update:

proportions of ergocristine, ergocornine and ergocryptine, the latter being a 2:1 mixture of alpha- and beta-ergocryptine. Ergotoxine group (valine as the amino...

Word Count : 2424

C32H41N5O5

Last Update:

formula C32H41N5O5 (molar mass: 575.710 g/mol) may refer to: Ergocryptine beta-Ergocryptine This set index page lists chemical structure articles associated...

Word Count : 51

Medicinal uses of fungi

Last Update:

these include ergotamine, dihydroergotamine, ergometrine, ergocristine, ergocryptine, ergocornine, methysergide, bromocriptine, cabergoline, and pergolide...

Word Count : 1718

Indole alkaloid

Last Update:

and their isomers Ergotoxine group, including ergocristine, α-ergocryptine, β-ergocryptine, ergocornine and their isomers. Ergotinine, discovered in 1875...

Word Count : 3376

Ergocornine

Last Update:

Lidbrink P, Ungerstedt U (April 1974). "Ergocornine and 2-Br-alpha-ergocryptine. Evidence for prolonged dopamine receptor stimulation". Medical Biology...

Word Count : 103

Fungal isolate

Last Update:

extremophile (Berkeley Pit, Montana) spiroketal anticancer compound beta-Ergocryptine ergot dopaminergic ergot alkaloid Bisvertinolone Trichoderma anticancer...

Word Count : 966

Ergoloid

Last Update:

16 (Suppl 3): 1–17. PMID 2869188. Rowell PP, Larson BT (July 1999). "Ergocryptine and other ergot alkaloids stimulate the release of [3H]dopamine from...

Word Count : 979

Dihydroergocryptine

Last Update:

group, which is a consequence of the biosynthesis of the parent compound ergocryptine, in which the proteinogenic amino acid leucine is replaced by isoleucine...

Word Count : 1532
PDF Search Engine © AllGlobal.net