Epithelial basement membrane dystrophy information
Medical condition
Epithelial basement membrane dystrophy
Other names
Map-dot-fingerprint dystrophy and Cogans's microcystic dystrophy
Specialty
Ophthalmology
Epithelial basement membrane dystrophy (EBMD) is a disorder of the eye that can cause pain and dryness.
It is sometimes included in the group of corneal dystrophies.[1] It diverges from the formal definition of corneal dystrophy since it is non-familial in most cases. It also has a fluctuating course, while for a typical corneal dystrophy the course is progressive. When it is considered part of this group, it is the most common type of corneal dystrophy.[2]
^Online Mendelian Inheritance in Man, #121820: Corneal dystrophy, epithelial basement membrane; EBMD, archived from the original on 2017-04-30.
^Chan, Colin (2015-02-18). Dry Eye: A Practical Approach. Springer. pp. 111–112. ISBN 9783662441060.
and 23 Related for: Epithelial basement membrane dystrophy information
Epithelialbasementmembranedystrophy (EBMD) is a disorder of the eye that can cause pain and dryness. It is sometimes included in the group of corneal...
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options. Those with Fuchs' corneal endothelial dystrophy, corneal epithelialbasementmembranedystrophy, retinal tears, autoimmune diseases, severe dry...
extracellular matrix. Abnormal laminin-332, essential for epithelial cell adhesion to the basementmembrane, leads to junctional epidermolysis bullosa, characterized...
failure of the cornea's outermost layer of epithelial cells to attach to the underlying basementmembrane (Bowman's layer). The condition is excruciatingly...
Benedek) Descemet's membrane (also posterior limiting membrane): a thin acellular layer that serves as the modified basementmembrane of the corneal endothelium...
or Boxer ulcers. They are believed to be caused by a defect in the basementmembrane and a lack of hemidesmosomal attachments. They are recognized by undermined...
embryo contributes to the formation of Reichert’s membrane, a thick extra-embryonic basementmembrane. When the laminin α1 chain is deficient in an organism...
vulva that shows dysplasia with varying degrees of atypia. The epithelialbasementmembrane is intact and the lesion is thus not invasive but has invasive...
separate easily. Posterior to the stroma is Descemet's membrane, which is a basementmembrane for the corneal endothelium. The endothelium is a single...
tissues. During epithelial morphogenesis of kidney, the dystroglycan complex is shown to act as a receptor for the basementmembrane. Dystroglycan expression...
Alport's syndrome is associated with RP and an abnormal glomerular-basementmembrane leading to nephrotic syndrome. It is inherited as X-linked dominant...
Occasionally the healed epithelium may be poorly adherent to the underlying basementmembrane in which case it may detach at intervals giving rise to recurrent...
frequent form of corneal dystrophy. In keratoconic corneas they have been shown to commit apoptosis far away from any epithelial injury; a hypothesis exists...
organized, polar cells. These cells are separated from stromal cells by a basementmembrane that prevents these cell populations from mixing. A mixture of these...
metalloproteinase degrades the cornea's basementmembrane and extracellular matrix, while proteolytic enzymes allow vascular epithelial cells to enter the stromal...
associated with laser in situ keratomileusis in patients with epithelialbasementmembranedystrophy. Am J Ophthalmol 2000;130:297-303. Lumba J, Hersh PS. Topography...
non-correct binding between pikachurin and DG is associated with muscular dystrophies that often involve eye abnormalities. Pikachurin is an extracellular...
universities. His research focuses on the basementmembranes, which interface between the overlying epithelial tissues and the underlying connective tissue...
deposits of the same material that originally damaged the glomerular basementmembrane in the kidneys. The diagnosis usually starts with a dilated examination...
From closest to farthest from the vitreous body: Inner limiting membrane – basementmembrane elaborated by Müller cells Nerve fibre layer – axons of the ganglion...
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