"EDAR" redirects here. For other uses, see EDAR (disambiguation).
Ectodysplasin A receptor (EDAR) is a protein that in humans is encoded by the EDAR gene. EDAR is a cell surface receptor for ectodysplasin A which plays an important role in the development of ectodermal tissues such as the skin.[1][2][3] It is structurally related to members of the TNF receptor superfamily.[4]
^Monreal AW, Ferguson BM, Headon DJ, Street SL, Overbeek PA, Zonana J (August 1999). "Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia". Nature Genetics. 22 (4): 366–9. doi:10.1038/11937. PMID 10431241. S2CID 11348633.
^Aswegan AL, Josephson KD, Mowbray R, Pauli RM, Spritz RA, Williams MS (November 1997). "Autosomal dominant hypohidrotic ectodermal dysplasia in a large family". American Journal of Medical Genetics. 72 (4): 462–7. doi:10.1002/(SICI)1096-8628(19971112)72:4<462::AID-AJMG17>3.0.CO;2-P. PMID 9375732.
^"Entrez Gene: EDAR ectodysplasin A receptor".
^Online Mendelian Inheritance in Man (OMIM): 604095
and 26 Related for: Ectodysplasin A receptor information
EctodysplasinAreceptor (EDAR) is a protein that in humans is encoded by the EDAR gene. EDAR is a cell surface receptor for ectodysplasinA which plays...
factor receptor superfamily member 27 is a protein that in humans is encoded by the EDA2R gene. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that...
recognized by the ectodysplasinAreceptor. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form...
Ectodysplasin-Areceptor-associated adapter protein is a protein that in humans is encoded by the EDARADD gene. This gene was identified by its association...
The tumor necrosis factor receptor superfamily (TNFRSF) is a protein superfamily of cytokine receptors characterized by the ability to bind tumor necrosis...
VM (March 2002). "Identification of a novel death domain-containing adaptor molecule for ectodysplasin-Areceptor that is mutated in crinkled mice". Curr...
Edar or EDAR may refer to: Edar (Bible), a tower EctodysplasinAreceptor, a protein E.D.Ar., an abbreviation for the United States District Court for...
of insect wing segment naming A-box 2 of insulin gene HLA-A2, a human MHC HLA-A serotype gene Ectodysplasin A2 receptor, a protein that in humans is encoded...
003. PMID 26476248. Hillmer A (2009-04-17). "Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship...
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
have been found to be linked to the ectodysplasinAreceptor gene (EDAR). EDAR is a functional genomic region and has a range of pleiotropic effects on ectodermally...
These fishes mostly eat live prey fishes because they have low EctodysplasinAReceptor(EDAR) and very few gill rakers. In some species, larvae are cannibals...
Nöthen MM (2009). "Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness"...
factor receptor 1 (TNFR1), also known as tumor necrosis factor receptor superfamily member 1A (TNFRSF1A) and CD120a, is a ubiquitous membrane receptor that...
forming a 'jelly roll' β-structure, typical for the TNF family, but also found in viral capsid proteins. TNF can bind two receptors, TNFR1 (TNF receptor type...
factor receptor 2 (TNFR2), also known as tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) and CD120b, is one of two membrane receptors that...
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of soluble versus membrane-associated LT. As a member of the TNF family, LT-α binds to various receptors and activates the NF-κB pathway, thus promoting...
Lymphotoxin beta receptor (LTBR), also known as tumor necrosis factor receptor superfamily member 3 (TNFRSF3), is a cell surface receptor for lymphotoxin...
including inflammation and activation signaling. Upon binding to the LTβ receptor, LT-αβ transmits signals leading to proliferation, homeostasis and activation...
the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasinA". J. Biol. Chem. 276 (4): 2668–77. doi:10.1074/jbc.M008356200. PMID 11035039...
69504326-69532508. Genetic neighbors include the gene EDA (ectodysplasinA) downstream and a long intergenic non-protein coding RNA upstream. The full...
efficacy. APO200 is a therapeutic recombinant protein that is developed from the ectodysplasinA-1 (EDA1) gene. This product is used to treat a rare human genetic...
beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of...
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