Ischemic bone disease caused by decompression bubbles
Medical condition
Dysbaric osteonecrosis
Specialty
Diving medicine, occupational medicine
Dysbaric osteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N2) embolism (blockage of the blood vessels by a bubble of nitrogen coming out of solution) in divers.[1] Although the definitive pathologic process is poorly understood, there are several hypotheses:
Intra- or extravascular nitrogen in bones, "nitrogen embolism".[citation needed]
Osmotic gas effects due to intramedullary pressure effects.[citation needed]
fat embolism[citation needed]
hemoconcentration and increased coagulability.[citation needed]
^Brubakk, Alf O; Neuman. Tom S (2003). Bennett and Elliott's physiology and medicine of diving, 5th Rev ed. United States: Saunders Ltd. p. 800. ISBN 978-0-7020-2571-6.
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Dysbaricosteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N2)...
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until after reaching the surface.[page needed] Bone degeneration (dysbaricosteonecrosis) is caused by the bubbles forming inside the bones; most commonly...