A migrating D. discoideum whose boundary is colored by curvature, scale bar: 5 µm, duration: 22 seconds
Scientific classification
Domain:
Eukaryota
Phylum:
Amoebozoa
Class:
Dictyostelia
Order:
Dictyosteliida
Family:
Dictyosteliidae
Genus:
Dictyostelium
Species:
D. discoideum
Binomial name
Dictyostelium discoideum
Raper, 1935[1]
Life cycle
Dictyostelium discoideum is a species of soil-dwelling amoeba belonging to the phylum Amoebozoa, infraphylum Mycetozoa. Commonly referred to as slime mold, D. discoideum is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its lifetime. Its unique asexual life cycle consists of four stages: vegetative, aggregation, migration, and culmination. The life cycle of D. discoideum is relatively short, which allows for timely viewing of all stages. The cells involved in the life cycle undergo movement, chemical signaling, and development, which are applicable to human cancer research. The simplicity of its life cycle makes D. discoideum a valuable model organism to study genetic, cellular, and biochemical processes in other organisms.[2]
^Raper, K.B. (1935). "Dictyostelium discoideum, a new species of slime mold from decaying forest leaves". Journal of Agricultural Research. 50: 135–147. Archived from the original on 2017-12-08. Retrieved 2016-01-20.
^Pears, Catherine J.; Gross, Julian D. (2021-03-01). "Microbe Profile: Dictyostelium discoideum: model system for development, chemotaxis and biomedical research". Microbiology. 167 (3). doi:10.1099/mic.0.001040. ISSN 1350-0872. PMID 33646931. S2CID 232092012.
and 27 Related for: Dictyostelium discoideum information
Dictyosteliumdiscoideum is a species of soil-dwelling amoeba belonging to the phylum Amoebozoa, infraphylum Mycetozoa. Commonly referred to as slime mold...
amoebae. In Dictyosteliumdiscoideum, aggregation is signalled by cAMP, but others use different chemicals. In the species Dictyostelium purpureum, the...
themselves to become a dead stalk, lifting the spores up into the air. Dictyosteliumdiscoideum is a microscopic organism. The cells can aggregate to form a grex...
dysentery, and the multicellular "social amoeba" or slime mould Dictyosteliumdiscoideum. Amoeba do not have cell walls, which allows for free movement...
development; overexpression in effector sites in lethal. Essential in Dictyosteliumdiscoideum. This is evidenced by severe developmental failure in deficient...
There are two strains of Pseudomonas fluorescens associated with Dictyosteliumdiscoideum. One strain serves as a food source and the other strain does not...
antimicrobial activities. Keanumycin A is active against the amoebas Dictyosteliumdiscoideum (IC50 = 4.4 nM), Acanthamoeba castellanii (IC50 = 2.0 μM), and...
advanced methods for genetic transformation and selection of genes. Dictyosteliumdiscoideum is used in molecular biology and genetics, and is studied as an...
history of life. Some organisms are partially unicellular, like Dictyosteliumdiscoideum. Additionally, unicellular organisms can be multinucleate, like...
in Macromycetozoa.[citation needed] Conosa includes the species Dictyosteliumdiscoideum, a social amoeba, and Entamoeba histolytica, a human pathogen,...
activate small Ras-like GTPase proteins, such as Rap1. In the species Dictyosteliumdiscoideum, cAMP acts outside the cell as a secreted signal. The chemotactic...
full-length cDNA libraries of small RNAs (sRNA) from the social amoeba Dictyosteliumdiscoideum. The RNAs are 59–60 nucleotides in length. A Northern blot analysis...
Smith SS, Rather DI (July 1991). "Lack of 5-methylcytosine in Dictyosteliumdiscoideum DNA". The Biochemical Journal. 277 (1): 273–275. doi:10.1042/bj2770273...
single alpha helix (SAH) Myosin VII is required for phagocytosis in Dictyosteliumdiscoideum, spermatogenesis in C. elegans and stereocilia formation in mice...
share many specific functions with mammalian phagocytic cells. Dictyosteliumdiscoideum, for example, is an amoeba that lives in the soil and feeds on...
early evolutionary cell sorting, with application to slime mold Dictyosteliumdiscoideum.” Journal of Theoretical Biology 469 (2019): 75–95 . Trenchard...
homothallic mating. An analysis of meiosis-related genes in the Dictyosteliumdiscoideum genome revealed that 36 of the 44 genes tested were present in...
sequencing approach of full-length cDNA libraries from small RNAs from Dictyosteliumdiscoideum. The function of this RNA is unknown, but it bears some resemblance...
PMC 3016996. PMID 20874599. "First of six chromosomes sequenced in Dictyosteliumdiscoideum". Genome News Network. Retrieved 2009-04-29. Zhang Y, Cheng C,...
coupled receptors. These receptors control development in Dictyosteliumdiscoideum. In D. discoideum, the cyclic AMP receptors coordinate aggregation of individual...
eukaryotic cells are observed to migrate similarly. The amoeba Dictyosteliumdiscoideum is useful to researchers because they consistently exhibit chemotaxis...
vacuoles per cell varies, depending on the species. Amoeba have one, Dictyosteliumdiscoideum, Paramecium aurelia and Chlamydomonas reinhardtii have two, and...
acrasins to be identified was cyclic AMP, found in the species Dictyosteliumdiscoideum by Brian Shaffer,[2] which exhibits a complex swirling-pulsating...
much faster than professional phagocytes. For the soil amoeba Dictyosteliumdiscoideum, their main food source is the bacteria Legionella pneumophila...
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