This article relies largely or entirely on a single source. Relevant discussion may be found on the talk page. Please help improve this article by introducing citations to additional sources. Find sources: "Deuterium NMR" – news · newspapers · books · scholar · JSTOR(March 2015)
Deuterium NMR is NMR spectroscopy of deuterium (2H or D), an isotope of hydrogen.[1]
Deuterium is an isotope with spin = 1, unlike hydrogen-1, which has spin = 1/2. The term deuteron NMR, in direct analogy to proton NMR, is also used.[2] Deuterium NMR has a range of chemical shift similar to proton NMR but with poor resolution, due to the smaller magnitude of the magnetic dipole moment of the deuteron relative to the proton. It may be used to verify the effectiveness of deuteration: a deuterated compound will show a strong peak in deuterium NMR but not proton NMR.
Deuterium NMR spectra are especially informative in the solid state because of its relatively small quadrupole moment in comparison with those of bigger quadrupolar nuclei such as chlorine-35, for example. This allows for the whole spectrum to be excited with practically achievable pulses of a few microseconds in duration. However, since the natural abundance of 2H is only 0.016%, the sample must usually be isotope enriched with 2H to achieve a sufficiently strong signal. For a given C-D moiety, the quadrupolar splitting in the 2H NMR spectrum depends in a simple way on the angle between the C-D bond and the applied static magnetic field.[2] Thus, 2H NMR can probe orientation distributions in partially ordered deuterated polymers.[2] Changes in C-D bond orientation due to molecular motions have pronounced effects on the spectral line shape.[2] One example is the use of deuterium NMR to study lipid membrane phase behavior.
^Mantsch, Henry H.; Saitô, Hazime; Smith, Ian C. P. (1977). "Deuterium magnetic resonance, applications in chemistry, physics and biology". Progress in Nuclear Magnetic Resonance Spectroscopy. 11 (4): 211–272. doi:10.1016/0079-6565(77)80010-1. ISSN 0079-6565.
^ abcdSpiess, H. W. (1985). "Deuteron NMR – A new Tool for Studying Chain Mobility and Orientation in Polymers", Advances in Polymer Science66: 23-57. DOI: 10.1007/3-540-13779-3_16.
DeuteriumNMR is NMR spectroscopy of deuterium (2H or D), an isotope of hydrogen. Deuterium is an isotope with spin = 1, unlike hydrogen-1, which has...
in protium NMR to prevent the solvent from overlapping with the signal, though deuteriumNMR on its own right is also possible. Deuterium is thought to...
self-assembly using deuteriumNMR spectroscopy. Much of the innovation within NMR spectroscopy has been within the field of protein NMR spectroscopy, an...
nucleus). Simple NMR spectra are recorded in solution, and solvent protons must not be allowed to interfere. Deuterated (deuterium = 2H, often symbolized...
biochemical studies, notably in NMR spectroscopy such as proton NMR, carbon-13 NMR, deuteriumNMR and phosphorus-31 NMR. Biochemical information can also...
variations of deuterium within identical compounds from different sources and hypothesized that NMR could be used to measure deuterium kinetic isotope...
heavy water (deuterium oxide = D2O) which is used in particle research, in deuteriumNMR spectroscopy, deuterated solvents for proton NMR spectroscopy...
Heavy water (deuterium oxide, 2 H 2O, D 2O) is a form of water whose hydrogen atoms are all deuterium (2 H or D, also known as heavy hydrogen) rather than...
O=C(CCl3)2 + D2O → 2 CDCl3 + CO2 In proton NMR spectroscopy, deuterated solvent (enriched to >99% deuterium) is typically used to avoid recording a large...
atoms ("H") are replaced with their isotope deuterium ("D"). Deuterated DMSO is a common solvent used in NMR spectroscopy. Deuterated DMSO is produced by...
spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the...
spectroscopy. Deuterium has a different magnetic moment and spin than protium, but generally a much smaller signal. Historically, deuteriumNMR is a poor...
D. 1981, M.P.H. 1981), physician, surgeon, and inventor of NMR microscopy and DeuteriumNMR spectroscopy Jeremy M. Berg (B.S. 1980), director of the National...
Perturbation by the Lipopeptide Surfactin and Detergents as Studied by DeuteriumNMR". The Journal of Physical Chemistry B. 108 (15): 4909–4915. doi:10.1021/jp0371938...
to study the properties of polymer gels by means of high-resolution deuteriumNMR, but only lately gel alignment was used to induce RDCs in molecules...
scale correctly, i.e. the solvent signal in the deuterium (lock) channel can be used to reference the a 1H NMR spectrum. Both indirect and direct referencing...
application of SNIF-NMR, it measures the ratio of deuterium/hydrogen on each site of a sample molecule The Carbon nuclei: 13C-SNIF-NMR method has opened...
atoms linked by a covalent bond. If we neglect the small proportion of deuterium and tritium which may be present, each hydrogen atom consists of one proton...
intermolecular structural elements can be investigated e.g. via deuterium REDOR (an established solid state NMR pulse sequence to measure dipolar couplings between...
group of compounds where one or more hydrogen atoms are substituted by deuterium atoms. These isotopologues of common solvents are often used in nuclear...
which the hydrogen atoms (H) are deuterium (heavy hydrogen) (2H or D). Deuterated DCM is not a common solvent used in NMR spectroscopy as it is expensive...
smaller peak may appear on top of each peak due to deuterium exchange from the D2O normally added to an NMR sample, giving these sidechain peaks a distinctive...
atom (H) is replaced with deuterium (heavy hydrogen) isotope (2H or D). Deuterated acetone is a common solvent used in NMR spectroscopy. As with all deuterated...
neopentane molecule can be broken if some hydrogen atoms are replaced by deuterium atoms. In particular, if each methyl group has a different number of substituted...
atoms ("H") are replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated methanol is a common solvent used in NMR spectroscopy. Deuterated methanol...
phenol (C6H5OH) in water by replacing common hydrogen (protium) with deuterium (deuterium labeling). Upon adding phenol to deuterated water (water containing...
atom ("H") is replaced with deuterium (heavy hydrogen) isotope ("D"). Deuterated ethanol is an uncommon solvent used in NMR spectroscopy. "Ethanol-d6"...
called heavy water. Deuterium and its compounds are used as a non-radioactive label in chemical experiments and in solvents for 1 H-NMR spectroscopy. Heavy...
Global Information