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Denervation supersensitivity information


Denervation supersensitivity/Denervation hypersensitivity is the sharp increase of sensitivity of postsynaptic membranes to a chemical transmitter after denervation.[1][2] It is a compensatory change.[3]

  1. ^ S. Thesleff, L.C. Sellin, "Denervation supersensitivity", Trends in Neurosciences, Volume 3, Issue 5, May 1980, Pages 122-126 doi:10.1016/0166–2236(80)90046-6
  2. ^ S. Z. Langer, "Denervation Supersensitivity", in: Principles of Receptor Research Volume 2 of the series Handbook of Psychopharmacology pp 245-280
  3. ^ Meurant, G. (1983). INTERNATIONAL REVIEW OF RESEARCH IN MENTAL RETARDATION. Elsevier Science. p. 151. ISBN 9780080857893.

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Denervation supersensitivity

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Denervation supersensitivity/Denervation hypersensitivity is the sharp increase of sensitivity of postsynaptic membranes to a chemical transmitter after...

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Denervation

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Denervation is any loss of nerve supply regardless of the cause. If the nerves lost to denervation are part of the neuronal communication to a specific...

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Supersensitivity

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Supersensitivity may refer to: Denervation supersensitivity Supersensitivity psychosis Disuse supersensitivity Hyperesthesia, abnormal increase in sensitivity...

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Substance P

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post-synaptic receptors. This, ultimately, leads to a condition known as denervation supersensitivity as the post-synaptic nerves will become hypersensitive to any...

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Disuse supersensitivity

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Disuse supersensitivity, also pharmacological disuse supersensitivity or pharmacological denervation supersensitivity, is the increased sensitivity by...

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Endoscopic thoracic sympathectomy

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Stroke. He has documented loss of thermoregulatory function, cardiac denervation, and loss of vasoconstriction. Recurrence of the original symptoms due...

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Adie syndrome

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pilocarpine may constrict the tonic pupil due to cholinergic denervation supersensitivity. A normal pupil will not constrict with the dilute dose of pilocarpine...

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Spinal shock

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reflexes return is the hypersensitivity of reflex muscles following denervation – more receptors for neurotransmitters are expressed and are therefore...

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Histamine

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against the susceptibility to convulsion, drug sensitization, denervation supersensitivity, ischemic lesions and stress. It has also been suggested that...

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Ciliary ganglion

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irregular contour to the pupil. (4) Denervation supersensitivity. Like any denervated muscle, the iris becomes supersensitive to its normal neurotransmitter...

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HDAC9

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(MEF2) and class I HDACs. By contrast, Hdac9-null mice are supersensitive to denervation-induced changes in gene expression and show chromatin hyperacetylation...

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