Large-scale brain network active when not focusing on an external task
Default mode network
fMRI scan showing regions of the default mode network; the dorsal medial prefrontal cortex, the posterior cingulate cortex, the precuneus and the angular gyrus
Identifiers
MeSH
D000082702
Anatomical terminology
[edit on Wikidata]
Default mode network connectivity. This image shows main regions of the default mode network (yellow) and connectivity between the regions color-coded by structural traversing direction (xyz → rgb).[1][2]
In neuroscience, the default mode network (DMN), also known as the default network, default state network, or anatomically the medial frontoparietal network (M-FPN), is a large-scale brain network primarily composed of the dorsal medial prefrontal cortex, posterior cingulate cortex, precuneus and angular gyrus. It is best known for being active when a person is not focused on the outside world and the brain is at wakeful rest, such as during daydreaming and mind-wandering. It can also be active during detailed thoughts related to external task performance.[3] Other times that the DMN is active include when the individual is thinking about others, thinking about themselves, remembering the past, and planning for the future.[4][5]
The DMN was originally noticed to be deactivated in certain goal-oriented tasks and was sometimes referred to as the task-negative network,[6] in contrast with the task-positive network. This nomenclature is now widely considered misleading, because the network can be active in internal goal-oriented and conceptual cognitive tasks.[7][8][9][10] The DMN has been shown to be negatively correlated with other networks in the brain such as attention networks.[11]
Evidence has pointed to disruptions in the DMN of people with Alzheimer's disease and autism spectrum disorder.[4]
^Horn, Andreas; Ostwald, Dirk; Reisert, Marco; Blankenburg, Felix (2013). "The structural-functional connectome and the default mode network of the human brain". NeuroImage. 102: 142–151. doi:10.1016/j.neuroimage.2013.09.069. PMID 24099851. S2CID 6455982.
^Garrity, A.; Pearlson, G. D.; McKiernan, K.; Lloyd, D.; Kiehl, K. A.; Calhoun, V. D. (2007). "Aberrant default mode functional connectivity in schizophrenia". Am. J. Psychiatry. 164 (3): 450–457. doi:10.1176/ajp.2007.164.3.450. PMID 17329470.
^Sormaz, Mladen; Murphy, Charlotte; Wang, Hao-Ting; Hymers, Mark; Karapanagiotidis, Theodoros; Poerio, Giulia; Margulies, Daniel S.; Jefferies, Elizabeth; Smallwood, Jonathan (2018). "Default mode network can support the level of detail in experience during active task states". Proceedings of the National Academy of Sciences. 115 (37): 9318–9323. Bibcode:2018PNAS..115.9318S. doi:10.1073/pnas.1721259115. PMC 6140531. PMID 30150393.
^ abCite error: The named reference Buckner was invoked but never defined (see the help page).
^Lieberman, Matthew (2 September 2016). Social. Broadway Books. p. 19. ISBN 978-0-307-88910-2.
^Fox, Michael D.; Snyder, Abraham Z.; Vincent, Justin L.; Corbetta, Maurizio; Van Essen, David C.; Raichle, Marcus E. (5 July 2005). "The human brain is intrinsically organized into dynamic, anticorrelated functional networks". Proceedings of the National Academy of Sciences of the United States of America. 102 (27): 9673–9678. Bibcode:2005PNAS..102.9673F. doi:10.1073/pnas.0504136102. ISSN 0027-8424. PMC 1157105. PMID 15976020.
^Spreng, R. Nathan (1 January 2012). "The fallacy of a "task-negative" network". Frontiers in Psychology. 3: 145. doi:10.3389/fpsyg.2012.00145. ISSN 1664-1078. PMC 3349953. PMID 22593750.
^Fortenbaugh, FC; DeGutis, J; Esterman, M (May 2017). "Recent theoretical, neural, and clinical advances in sustained attention research". Annals of the New York Academy of Sciences. 1396 (1): 70–91. Bibcode:2017NYASA1396...70F. doi:10.1111/nyas.13318. PMC 5522184. PMID 28260249.
^Murphy, C; Jefferies, E; Rueschemeyer, SA; Sormaz, M; Wang, HT; Margulies, DS; Smallwood, J (1 May 2018). "Distant from input: Evidence of regions within the default mode network supporting perceptually-decoupled and conceptually-guided cognition". NeuroImage. 171: 393–401. doi:10.1016/j.neuroimage.2018.01.017. PMC 5883322. PMID 29339310.
^Cite error: The named reference Uddin-UniversalTaxonomy-2019 was invoked but never defined (see the help page).
^Cite error: The named reference Broyd was invoked but never defined (see the help page).
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posterior cingulate, precuneus, and medial prefrontal areas of the defaultmodenetwork, but also in non-cortical areas near the ventricles, cisterns and...
forms a central node in the defaultmodenetwork of the brain. It has been shown to communicate with various brain networks simultaneously and is involved...
dysfunction in the sensorimotor network (SMN) and its balance with other large-scale networks such as the defaultmodenetwork. Amyotrophic Lateral Sclerosis:...
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DMN or dmn may refer to: Defaultmodenetwork, a network of brain regions Dorsal motor nucleus, a nerve nucleus for the vagus nerve Dorsomedial nucleus...
port on the server (default port: 5900). Alternatively (depending on the implementation) a browser can connect to the server (default port: 5800). And a...
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