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Cytostasis information


Cytostasis (cyto – cell; stasis – stoppage) is the inhibition of cell growth and multiplication. Cytostatic refers to a cellular component or medicine that inhibits cell division.

Cytostasis is an important prerequisite for structured multicellular organisms. Without regulation of cell growth and division only unorganized heaps of cells would be possible.

Chemotherapy of cancer, treatment of skin diseases and treatment of infections are common use cases of cytostatic drugs. Active hygienic products generally contain cytostatic substances.

Cytostatic mechanisms and drugs generally occur together with cytotoxic ones.

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Cytostasis

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(NO), which induces both cytostasis and cytotoxicity to tumor cells both in vitro and in vivo. Nitric oxide-induced cytostasis targets ribonucleotide reductase...

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Pathogenic fungus

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supports the role of these molecules as effectors of macrophage-mediated cytostasis". Infect. Immun. 59 (7): 2291–6. doi:10.1128/IAI.59.7.2291-2296.1991....

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Chemotherapy

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Cancer and nausea Cancer-related fatigue Chemo brain Chemotherapy regimens Cytostasis Experimental cancer treatments Safe Handling of Hazardous Drugs Drug delivery...

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National Cancer Institute

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potency, and demonstration of a unique pattern of cellular cytotoxicity or cytostasis, indicating a unique mechanism of action or intracellular target. A high...

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Cryptococcus neoformans

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supports the role of these molecules as effectors of macrophage-mediated cytostasis". Infect Immun. 59 (7): 2291–2296. doi:10.1128/IAI.59.7.2291-2296.1991...

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Micronucleus

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later evolved into the CBMN 'cytome' assay to further explore cell death, cytostasis, and biomarkers of DNA damage. The major drawback of using micronucleus...

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Guanylate cyclase 2C

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guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis". Mol. Cell. Biol. 29 (19): 5277–89. doi:10.1128/MCB.00001-09. PMC 2747985...

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Oncostatin M receptor

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PMID 28288136. Underhill-Day N, Heath JK (November 2006). "Oncostatin M (OSM) cytostasis of breast tumor cells: characterization of an OSM receptor beta-specific...

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Obesity and cancer

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Arıbas S, Gundogan K, Diri H (2014). "Evaluation of chromosomal damage, cytostasis, cytotoxicity, oxidative DNA damage and their association with body-mass...

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Agent study

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studies are used to determine whether a substance exhibits cytotoxicity or cytostasis. A cytotoxic agent will shrink a tumor, while, a cytostatic agent slows...

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