Cyclopropylfentanyl information

Cyclopropylfentanyl
Legal status
Legal status	BR: Class F1 (Prohibited narcotics); CA: Schedule I; DE: Anlage II (Authorized trade only, not prescriptible); UK: Class A; US: Schedule I; Illegal in the European Union;
Identifiers
	IUPAC name N-Phenyl-N-[1-(2-Phenylethyl)piperidin-4-yl]cyclopropanecarboxamide;
CAS Number	1169-68-2;
PubChem CID	137332271;
ChemSpider	81367233;
UNII	9R5A897QPI;
KEGG	C22757;
Chemical and physical data
Formula	C23H28N2O
Molar mass	348.490 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC1C(=O)N(C2CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4;
	InChI InChI=1S/C23H28N2O/c26-23(20-11-12-20)25(21-9-5-2-6-10-21)22-14-17-24(18-15-22)16-13-19-7-3-1-4-8-19/h1-10,20,22H,11-18H2; Key:OIQSKDSKROTEMN-UHFFFAOYSA-N;

Cyclopropylfentanyl is an opioid analgesic that is an analog of fentanyl and has been sold as a designer drug.^[1]^[2] Between June and December 2017, a total of 78 cyclopropylfentanyl-related deaths with analytical confirmation in post-mortem samples were reported by various European countries.^[3]^[4] Another 115 deaths involving cyclopropylfentanyl were reported from the United States in 2017.^[5]

^ Park K (20 December 2017). "2 arrested in drug scheme that funneled cyclopropyl fentanyl pills into Monmouth County". Asbury Park Press.
^ Edison L, Erickson A, Smith S, Lopez G, Hon S, King A, et al. (October 2017). "Notes from the Field: Counterfeit Percocet-Related Overdose Cluster - Georgia, June 2017". MMWR. Morbidity and Mortality Weekly Report. 66 (41): 1119–1120. doi:10.15585/mmwr.mm6641a6. PMC 5689089. PMID 29049275.
^ European Monitoring Centre for Drugs Drug Addiction; European Union Agency for Law Enforcement Cooperation (February 2018). Cyclopropylfentanyl : EMCDDA–Europol joint report on a new psychoactive substance : N-phenyl-N-1-(2-phenylethyl)piperidin-4-ylcyclopropanecarboxamide (cyclopropylfentanyl) : in accordance with Article 5 of Council Decision 2005/387/JHA on the information exchange, risk assessment and control of new psychoactive substances. Publications Office. doi:10.2810/06909. ISBN 9789294972545.
^ Wilde M, Sommer MJ, Auwärter V, Hermanns-Clausen M (March 2020). "Acute severe intoxication with cyclopropylfentanyl, a novel synthetic opioid". Toxicology Letters. 320: 109–112. doi:10.1016/j.toxlet.2019.11.025. PMID 31778775. S2CID 208356660.
^ "Schedules of Controlled Substances: Temporary Placement of Cyclopropyl Fentanyl in Schedule I". www.deadiversion.usdoj.gov. 4 January 2018.

[1] Park K (20 December 2017). "2 arrested in drug scheme that funneled cyclopropyl fentanyl pills into Monmouth County". Asbury Park Press.

[2] Edison L, Erickson A, Smith S, Lopez G, Hon S, King A, et al. (October 2017). "Notes from the Field: Counterfeit Percocet-Related Overdose Cluster - Georgia, June 2017". MMWR. Morbidity and Mortality Weekly Report. 66 (41): 1119–1120. doi:10.15585/mmwr.mm6641a6. PMC 5689089. PMID 29049275.

[3] European Monitoring Centre for Drugs Drug Addiction; European Union Agency for Law Enforcement Cooperation (February 2018). Cyclopropylfentanyl : EMCDDA–Europol joint report on a new psychoactive substance : N-phenyl-N-1-(2-phenylethyl)piperidin-4-ylcyclopropanecarboxamide (cyclopropylfentanyl) : in accordance with Article 5 of Council Decision 2005/387/JHA on the information exchange, risk assessment and control of new psychoactive substances. Publications Office. doi:10.2810/06909. ISBN 9789294972545.

[4] Wilde M, Sommer MJ, Auwärter V, Hermanns-Clausen M (March 2020). "Acute severe intoxication with cyclopropylfentanyl, a novel synthetic opioid". Toxicology Letters. 320: 109–112. doi:10.1016/j.toxlet.2019.11.025. PMID 31778775. S2CID 208356660.

[5] "Schedules of Controlled Substances: Temporary Placement of Cyclopropyl Fentanyl in Schedule I". www.deadiversion.usdoj.gov. 4 January 2018.

Cyclopropylfentanyl information

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Legal status


Legal status	BR: Class F1 (Prohibited narcotics) CA: Schedule I DE: Anlage II (Authorized trade only, not prescriptible) UK: Class A US: Schedule I Illegal in the European Union
Identifiers
IUPAC name N-Phenyl-N-[1-(2-Phenylethyl)piperidin-4-yl]cyclopropanecarboxamide
CAS Number	1169-68-2
PubChem CID	137332271
ChemSpider	81367233
UNII	9R5A897QPI
KEGG	C22757
Chemical and physical data
Formula	C₂₃H₂₈N₂O
Molar mass	348.490 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C1CC1C(=O)N(C2CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4
InChI InChI=1S/C23H28N2O/c26-23(20-11-12-20)25(21-9-5-2-6-10-21)22-14-17-24(18-15-22)16-13-19-7-3-1-4-8-19/h1-10,20,22H,11-18H2 Key:OIQSKDSKROTEMN-UHFFFAOYSA-N