"Sangre de Drago" redirects here. It may also refer to Jatropha dioica.
Croton lechleri
Scientific classification
Kingdom:
Plantae
Clade:
Tracheophytes
Clade:
Angiosperms
Clade:
Eudicots
Clade:
Rosids
Order:
Malpighiales
Family:
Euphorbiaceae
Genus:
Croton
Species:
C. lechleri
Binomial name
Croton lechleri
Müll.Arg.[1]
Croton lechleri is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known as sangre de grado (Peruvian Spanish), sangre de drago (Ecuadorian Spanish) or sangre de grada (Bolivian Spanish) .[2] They refer to this tree's (and several related species') thick red latex.[2][3]
The latex has medicinal properties, and is used by local peoples as a liquid bandage, applied to seal wounds, as it dries quickly to form a protective skin-like barrier.[4] Its use by native people has led to scientific study and observation of its in vitro antioxidant activity as well as both mutagenic[5] and antimutagenic[6] behavior.
The latex also contains a number of chemicals, including taspine.[7] Oligomeric proanthocyanidins, another kind of chemical contained in the latex, have been investigated for the treatment of HIV-associated diarrhea under the name crofelemer.[8] In January 2013, crofelemer, under the trade name Mytesi, was approved by the FDA for the treatment of non-infectious diarrhea in HIV+ patients.[9]
^"Croton lechleri". Germplasm Resources Information Network. Agricultural Research Service, United States Department of Agriculture. Retrieved 2012-07-07.
^ abMeza, E.N.(Editor). 1999.
^"Database File for: Sangre de Grado (Croton lechleri)". Tropical Plant Database. Rainforest Database. Retrieved 2012-07-07.
^Miller, Mark (2001). "Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado". Journal of Investigative Dermatology. 117 (3): 725–730. doi:10.1046/j.0022-202x.2001.01446.x. PMID 11564183.
^Lopes, M. I. L. E.; Saffi, J.; Echeverrigaray, S. R.; Henriques, J. O. A. P. G.; Salvador, M. (December 2004). "Mutagenic and antioxidant activities of Croton lechleri sap in biological systems". Journal of Ethnopharmacology. 95 (2–3): 437–445. doi:10.1016/j.jep.2004.08.025. PMID 15507372.
^Rossi, D.; Bruni, R.; Bianchi, N.; Chiarabelli, C.; Gambari, R.; Medici, A.; Lista, A.; Paganetto, G. (2003). "Evaluation of the mutagenic, antimutagenic and antiproliferative potential of Croton lechleri (Muell. Arg.) latex". Phytomedicine. 10 (2–3): 139–144. doi:10.1078/094471103321659843. hdl:11392/532990. PMID 12725567.
^Lopes, T. V.; Félix, S. R.; Schons, S. V.; Nobre, M. O. (January 2013). "Dragon's blood (Croton lechleri Mull., Arg.): an update on the chemical composition and medical applications of this natural plant extract. A review". Revista Brasileira de Higiene e Sanidade Animal. 7 (2): 167–191. doi:10.5935/1981-2965.20130016.
^Tradtrantip, L.; Namkung, W.; Verkman, A. S. (2009). "Crofelemer, an Antisecretory Antidiarrheal Proanthocyanidin Oligomer Extracted from Croton lechleri, Targets Two Distinct Intestinal Chloride Channels". Molecular Pharmacology. 77 (1): 69–78. doi:10.1124/mol.109.061051. PMC 2802429. PMID 19808995.
^"FDA approves first anti-diarrheal drug for HIV/AIDS patients". Food and Drug Administration. Dec 31, 2012.
Crotonlechleri is a species of flowering plant in the spurge family, Euphorbiaceae, that is native to northwestern South America. It is commonly known...
proanthocyanidin from "dragon's blood", the sap of the South American tree Crotonlechleri. Crofelemer treats the symptoms of disease, but it is not used to treat...
It is found in various plants including Magnolia x soulangeana and Crotonlechleri. The first total synthesis was reported by T. Ross Kelly and Roger...
approved by the FDA in 2012, an extract of "dragon's blood" sap of the Crotonlechleri plant, for diarrhea in people with HIV/AIDS Nabiximols (USAN, trade...
Glaucium oxylobum and Corydalis yanhusuo, and in other plants like Crotonlechleri in the family Euphorbiaceae. It has bronchodilator, neuroleptic and...
C and E, resveratrol and flavonoids (e.g. wine), Sangre de grado (Crotonlechleri) aka Dragons Blood, green and black teas, cloves, cinnamon, most commonly...
of yuca today, as well as medicine plants, such as sangre de grado (Crotonlechleri). Yine people speak the Yine language, which is a Piro language and...
procyanidins and prodelphinidins from the latex of the South American tree Crotonlechleri (locally called Sangre de Grado or Sangre de Drago) Porter, 1992 Rahima...