Surgical procedure of repairing corneal tissue to treat corneal blindness
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Corneal transplantation
Cornea transplant approximately one week after surgery. Multiple light reflections indicate folds in the cornea, which were later resolved.
Other names
Corneal grafting
ICD-9-CM
11.6
MeSH
D016039
MedlinePlus
003008
[edit on Wikidata]
Corneal transplantation, also known as corneal grafting, is a surgical procedure where a damaged or diseased cornea is replaced by donated corneal tissue (the graft). When the entire cornea is replaced it is known as penetrating keratoplasty and when only part of the cornea is replaced it is known as lamellar keratoplasty. Keratoplasty simply means surgery to the cornea. The graft is taken from a recently deceased individual with no known diseases or other factors that may affect the chance of survival of the donated tissue or the health of the recipient.
The cornea is the transparent front part of the eye that covers the iris, pupil and anterior chamber. The surgical procedure is performed by ophthalmologists, physicians who specialize in eyes, and is often done on an outpatient basis. Donors can be of any age, as is shown in the case of Janis Babson, who donated her eyes after dying at the age of 10.[1][2] Corneal transplantation is performed when medicines, keratoconus conservative surgery and cross-linking can no longer heal the cornea.
This surgical procedure usually treats corneal blindness,[3][4] with success rates of at least 41% as of 2021.[5][6][7]
^"Janis Babson". organdonorhalloffame. December 1961. Archived from the original on 2 March 2013. Retrieved 6 January 2022.
^"The influence of Janis Babson can be felt by many physicians". KevinMD.com. 15 February 2014. Archived from the original on 7 March 2014. Retrieved 6 January 2022.
^Maghsoudlou, Panayiotis; Sood, Gitanjli; Akhondi, Hossein (31 July 2021), "Cornea Transplantation", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 30969512, retrieved 6 January 2022
^Wong, Kah Hie; Kam, Ka Wai; Chen, Li Jia; Young, Alvin L. (18 July 2017). "Corneal blindness and current major treatment concern-graft scarcity". International Journal of Ophthalmology. 10 (7): 1154–1162. doi:10.18240/ijo.2017.07.21. ISSN 2222-3959. PMC 5514281. PMID 28730122.
^Holland, Gráinne; Pandit, Abhay; Sánchez-Abella, Laura; Haiek, Andrea; Loinaz, Iraida; Dupin, Damien; Gonzalez, Maria; Larra, Eva; Bidaguren, Aritz; Lagali, Neil; Moloney, Elizabeth B. (12 November 2021). "Artificial Cornea: Past, Current, and Future Directions". Frontiers in Medicine. 8: 2145. doi:10.3389/fmed.2021.770780. ISSN 2296-858X. PMC 8632951. PMID 34869489.
^Armitage, W. John; Goodchild, Christine; Griffin, Matthew D.; Gunn, David J.; Hjortdal, Jesper; Lohan, Paul; Murphy, Conor C.; Pleyer, Uwe; Ritter, Thomas; Tole, Derek M.; Vabres, Bertrand (19 November 2019). "High-risk Corneal Transplantation: Recent Developments and Future Possibilities". Transplantation. 103 (12): 2468–2478. doi:10.1097/TP.0000000000002938. ISSN 0041-1337. PMC 6867666. PMID 31765363.
^Reinprayoon, Usanee; Srihatrai, Parinya; Satitpitakul, Vannarut; Puangsricharern, Vilavun; Wungcharoen, Thitima; Kasetsuwan, Ngamjit (18 October 2021). "Survival Outcome and Prognostic Factors of Corneal Transplantation: A 15-Year Retrospective Cohort Study at King Chulalongkorn Memorial Hospital". Clinical Ophthalmology. 15: 4189–4199. doi:10.2147/OPTH.S336986. ISSN 1177-5467. PMC 8536876. PMID 34703206.
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