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Convulxin information


Convulxin is a snake venom toxin found in a tropical rattlesnake known as Crotalus durissus terrificus. It belongs to the family of hemotoxins, which destroy red blood cells or, as is the case with convulxin, induce blood coagulation. [citation needed]

Convulxin
Ring like protein α4β4 structure of convulxin
Identifiers
OrganismCrotalus durissus terrificus
SymbolCVX
CAS number37206-04-5
PDB1UMR
UniProtO93426
Search for
StructuresSwiss-model
DomainsInterPro

It causes platelet activation in the blood, forming clots and buildup of pressure. Convulxin acts as an agonist to the GPVI receptor, the major signalling receptor for collagen.[1] This can cause the blood stream to burst, or the heart or brain to lose blood, thus resulting in death. It is a tetramer C-type lectin with an oligomeric structure, made up of heterodimeric subunits.[2]

  1. ^ Cite error: The named reference Hermans_2009 was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference Polgár_1997 was invoked but never defined (see the help page).

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Convulxin

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Convulxin is a snake venom toxin found in a tropical rattlesnake known as Crotalus durissus terrificus. It belongs to the family of hemotoxins, which...

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Snake venom

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many cobra species: The tropical rattlesnake Crotalus durissus produces convulxin, a coagulant. Myotoxins are small, basic peptides found in rattlesnake...

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Platelet glycoprotein VI

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Clemetson KJ (May 1997). "Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake)...

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Atrolysin A

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aggregation such as adenosine diphosphate (ADP) or pathways mediated by convulxin also do not seem inhibited by the toxin in most organisms. The cysteine-rich...

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FYB

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proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin". The Journal of Biological Chemistry. 275 (43): 33427–33434. doi:10.1074/jbc...

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SKAP2

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proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin". The Journal of Biological Chemistry. 275 (43): 33427–34. doi:10.1074/jbc...

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