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Diagram of the uriniferous tubule and the blood vessels of the kidney. PC is the proximal convoluted tubule and IDC is the distal convoluted tubule
Convoluted tubule is the compound of a metanephridium which is wrapped with capillaries. It is highly coiled so as to increase surface area for more effective reabsorption, which occurs in this part of the metanephridium.
The distal tubule of the mammalian kidney is the portion of the nephron located between the macula densa region and the cortical collecting tubule. It consists of various subsegments that differ in structure and function, and it is responsible for reabsorbing 5-10% of filtered sodium and chloride under normal circumstances, as well as playing a significant role in potassium secretion. Additionally, this segment is crucial for maintaining systemic calcium and magnesium balance, as well as aiding in net acid secretion. Inherited disorders affecting the function of distal tubule cells can result in abnormalities in extracellular fluid volume, potassium, calcium, and magnesium levels, underscoring the importance of the distal tubule in human physiology and health conditions.
The distal convolutedtubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting tubule. It is partly responsible for the...
transition to proximal tubule epithelial cells (PTECs). The proximal tubule can be further classified into the proximal convolutedtubule (PCT) and the proximal...
Convolutedtubule is the compound of a metanephridium which is wrapped with capillaries. It is highly coiled so as to increase surface area for more effective...
The tubule has five anatomically and functionally different parts: the proximal tubule, which has a convoluted section the proximal convolutedtubule followed...
from the pulp cavity to the cementum or the enamel Distal convolutedtubule: the convoluted portion of the vertebrate nephron that lies between the loop...
testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that...
increased mobility Convolute laminations in geology Convolutedtubule, in anatomy Distal convolutedtubule Convolution (disambiguation) This disambiguation...
kidney. The effect of vasopressin on the kidney tubules is to reabsorb water from the distal convolutedtubules and collecting ducts, thus preventing aggravation...
Thiazide-type diuretics such as hydrochlorothiazide act on the distal convolutedtubule and inhibit the sodium-chloride symporter leading to a retention of...
(also known as NCC, NCCT, or TSC), which can be found in the distal convolutedtubule of the kidney. Disease-causing variants in SLC12A3 lead to a loss...
densa, in the distal straight tubule (thick ascending limb of the loop of Henle), after which the distal convolutedtubule begins juxtaglomerular cells...
known as the distal straight tubule, in contrast with the distal convolutedtubule downstream. The ascending limb of the loop of Henle is a direct continuation...
system. It is adjacent to the distal convolutedtubule, the most distal segment of the renal tubule. Connecting tubules from several adjacent nephrons merge...
inhibits sodium-glucose co-transporter 2 (SGLT-2) in the renal proximal convolutedtubule to reduce glucose reabsorption and increase urinary glucose excretion...
increasing water permeability in the collecting ducts and distal convolutedtubules; specifically, it acts on proteins called aquaporins and more specifically...
through the nephron. Selective reabsorbtion occurs in the PCT (proximal convolutedtubule). The PCT is highly permeable meaning it is easy for molecules to...
joined to neighboring cells. As with other regions, tubule cells in the distal convolutedtubule possess the ATP-powered sodium-potassium antiporter (Na+/K+-ATPase)...
species at physiological pH. Under normal conditions in the proximal convolutedtubule of the kidney, most of the carbonic acid (H2CO3) produced intracellularly...
arterioles, renal corpuscles, proximal convolutedtubules, macula densa, distal convolutedtubules, connecting tubules and the initial parts of the collecting...
present in the urine in certain disease states. They form in the distal convolutedtubule and collecting ducts of nephrons, then dislodge and pass into the...
(although the nephron often has a short intermediate segment between the convolutedtubules). It is only in mammals that the kidney takes on its classical "kidney"...
diuretics are 90% bonded to proteins and are secreted into the proximal convolutedtubule through organic anion transporter 1 (OAT-1), OAT-2, and ABCC4. Loop...
secretion occurs at Proximal ConvolutedTubule (PCT) and Distal ConvolutedTubule (D.C.T); for example, at proximal convolutedtubule, potassium is secreted...
Firstly, the glucose in the proximal tubule is co-transported with sodium ions into the proximal convolutedtubule walls via the SGLT2 cotransporter. Some...
by inhibiting sodium reabsorption at the beginning of the distal convolutedtubule (DCT). Water is lost as a result of more sodium reaching the collecting...
kidney tubules. The excess hemoglobin that is not bound to haptoglobin is filtered by the kidneys and reabsorbed in the proximal convolutedtubule, where...
syndrome affects the proximal tubules, namely, the proximal convolutedtubule (PCT), which is the first part of the tubule to process fluid after it is...
decreased arterial blood pressure, decreased sodium content in the distal convolutedtubule, and increased sympathetic tone. Renin initiates the downstream sequence...
nephron occurs in proximal convolutedtubule and at the ascending Loop of Henle. PTH acts on the distal convolutedtubule and collecting duct to increase...
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