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Compartmental neuron models information


Compartmental modelling of dendrites deals with multi-compartment modelling of the dendrites, to make the understanding of the electrical behavior of complex dendrites easier. Basically, compartmental modelling of dendrites is a very helpful tool to develop new biological neuron models. Dendrites are very important because they occupy the most membrane area in many of the neurons and give the neuron an ability to connect to thousands of other cells. Originally the dendrites were thought to have constant conductance and current but now it has been understood that they may have active Voltage-gated ion channels, which influences the firing properties of the neuron and also the response of neuron to synaptic inputs.[1] Many mathematical models have been developed to understand the electric behavior of the dendrites. Dendrites tend to be very branchy and complex, so the compartmental approach to understand the electrical behavior of the dendrites makes it very useful. [1][2]

  1. ^ a b Ermentrout, Bard; Terman H. David (2010). Mathematical Foundations of Neuroscience. Springer. pp. 29–45. ISBN 978-0-387-87707-5.
  2. ^ Lindsay, A. E., Lindsay, K. A., & Rosenberg, J. R. (2005). Increased computational accuracy in multi-compartmental cable models by a novel approach for precise point process localization. Journal of Computational Neuroscience, 19(1), 21–38.

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