Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Coenzyme Q10 (CoQ10/ˌkoʊkjuːˈtɛn/) also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by the human body.[1][2][3] It can also be obtained from dietary sources, such as meat, fish, seed oils, vegetables, and dietary supplements.[1][2] CoQ10 is found in many organisms, including animals and bacteria.
CoQ10 plays a role in mitochondrial oxidative phosphorylation, aiding in the production of adenosine triphosphate (ATP), which is involved in energy transfer within cells.[1] The structure of CoQ10 consists of a benzoquinone moiety and an isoprenoid side chain, with the "10" referring to the number of isoprenyl chemical subunits in its tail.[4][5][6]
Although a ubiquitous molecule in human tissues, CoQ10 is not a dietary nutrient, does not have a recommended intake level, and its use as a supplement is not associated with or approved for any health or anti-disease effect.[1][2]
^ abcd"Coenzyme Q10". Micronutrient Information Center, Linus Pauling Institute, Oregon State University. 2018. Archived from the original on 15 March 2024. Retrieved 13 April 2024.
^ abcSood B, Preeti Patel P, Keenaghan M (30 January 2024). "Coenzyme Q10". StatPearls, US National Library of Medicine. PMID 30285386. Archived from the original on 2 October 2023. Retrieved 17 April 2024.
^"Coenzyme Q10". National Center for Complementary and Integrative Health, US National Institutes of Health. January 2019. Archived from the original on 4 April 2024. Retrieved 13 April 2024.
^Mantle D, Lopez-Lluch G, Hargreaves IP (January 2023). "Coenzyme Q10 Metabolism: A Review of Unresolved Issues". International Journal of Molecular Sciences. 24 (3): 2585. doi:10.3390/ijms24032585. PMC 9916783. PMID 36768907. This article incorporates text from this source, which is available under the CC BY 4.0 license.
^Kadian M, Sharma G, Pandita S, Sharma K, Shrivasatava K, Saini N, et al. (2022). "The Impact of Coenzyme Q10 on Neurodegeneration: A Comprehensive Review". Current Pharmacology Reports. 8: 1–19. doi:10.1007/s40495-021-00273-6.
^Mantle D, Heaton RA, Hargreaves IP (May 2021). "Coenzyme Q10 and Immune Function: An Overview". Antioxidants. 10 (5): 759. doi:10.3390/antiox10050759. PMC 8150987. PMID 34064686. This article incorporates text from this source, which is available under the CC BY 4.0 license.
CoenzymeQ10 (CoQ10 /ˌkoʊkjuːˈtɛn/) also known as ubiquinone, is a naturally occurring biochemical cofactor (coenzyme) and an antioxidant produced by...
The International CoenzymeQ10 Association is a nonprofit association originally based in Ancona, Italy and currently in Seville, Spain. Since its establishment...
CoenzymeQ10 deficiency is a deficiency of coenzymeQ10. It can be associated with COQ2, APTX, PDSS2, PDSS1, CABC1, and COQ9. Some forms may be more treatable...
Q10 or Q-10 may refer to: Q10 (temperature coefficient) CoenzymeQ10, a dietary supplement BlackBerry Q10, a smartphone Q10 (New York City bus) MMIST...
multicenter study on the safety and efficacy of coenzymeQ10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators". Molecular Aspects...
researcher and the leading author for the Q-Symbio study of the "Effect of CoenzymeQ10 on Morbidity and Mortality in Chronic Heart Failure." Mortensen was one...
language Coq (software), an interactive theorem prover CoQ, common term for CoenzymeQ10, a naturally occurring biochemical cofactor and antioxidant produced...
coenzyme Q is 2,3-dimethoxy-5-methyl-6-poly prenyl-1,4-benzoquinol, where the polyprenylated side-chain is 9-10 units long in mammals. CoenzymeQ10 (CoQ10)...
Mitoquinone mesylate (MitoQ) is a synthetic analogue of coenzymeQ10 which has antioxidant effects. It was first developed in New Zealand in the late 1990s...
published journal articles on cholesterol[non-primary source needed] and coenzymeQ10.[non-primary source needed] He has appeared on national radio and television...
the inner mitochondrial membrane, the lipid-soluble electron carrier coenzymeQ10 (Q) carries both electrons and protons by a redox cycle. This small benzoquinone...
medications such as fibrates, and hypothyroidism. CoenzymeQ10 (ubiquinone) levels are decreased in statin use; CoQ10 supplements are sometimes used to treat statin-associated...
ballistoconidia that are bilaterally symmetrical, they have CoenzymeQ10 or CoenzymeQ10(H2) as their major ubiquinone, they lack xylose in whole-cell...
solanaceous species. It is notable as the biosynthetic precursor to coenzymeQ10. Solanesol is a non-cyclic terpene alcohol that consists of nine isoprene...
skin health, as well as reducing pore size. Horse ointment contains coenzymeQ10, hyaluronic acid, and collagen, which can maintain the natural moisture...
Moesgaard S, Hunter DA (2003). "Serum coenzymeQ10 concentrations in healthy men supplemented with 30 mg or 100 mg coenzymeQ10 for two months in a randomised...
increases in collagen turnover markers as well as a reduction in plasma coenzymeQ10 levels in patients with chronic heart failure. The dose-related magnitude...
COX-negative fibres, respiratory chain impairment, and deficiency of coenzymeQ10. Some forms of MADD respond well to riboflavin, known as riboflavin-responsive...
found. Plastoquinones are very structurally similar to ubiquinone, or coenzymeQ10, differing by the length of the isoprenyl side chain, replacement of...
diverse class of over 30,000 biomolecules such as cholesterol, vitamin K, coenzymeQ10, and all steroid hormones. The mevalonate pathway begins with acetyl-CoA...
bacteria to humans. It catalyzes the transfer of electrons from NADH to coenzymeQ10 (CoQ10) and translocates protons across the inner mitochondrial membrane...
performed in 2010, it was found that the water-soluble formulation of coenzymeQ10 (CoQ10) caused a significant improvement in liminar tonal audiometry of...
persist, as they can, in rare cases, develop into more serious problems. CoenzymeQ10 supplementation can be helpful to avoid some statin-related adverse effects...
UK market. In 1990, Pharma Nord was the first company to introduce a coenzymeQ10 product (ubiquinone) on the European market after it was discovered in...
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