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Chlordane information


Chlordane
cis-chlordane (α-chlordane)
trans-chlordane (γ-chlordane, beta-chlordane)
cis-chlordane
trans-chlordane
Names
Systematic IUPAC name
1,2,4,5,6,7,8,8-Octachloro-3a,4,7,7a-tetrahydro-4,7-methanoindane
Other names
Chlordan; Chlordano; Ortho; Octachloro-4,7-methanohydroindane
Identifiers
CAS Number
  • 57-74-9 checkY
ECHA InfoCard 100.000.317 Edit this at Wikidata
IUPHAR/BPS
  • 2831
KEGG
  • C14176 checkY
PubChem CID
  • 5993
UNII
  • A9RLM212CY checkY
CompTox Dashboard (EPA)
  • DTXSID7020267 Edit this at Wikidata
Properties
Chemical formula
C10H6Cl8
Molar mass 409.76 g·mol−1
Appearance White solid
Odor Slightly pungent, chlorine-like
Density 1.59 g/cm3
Melting point 102–106 °C (216–223 °F; 375–379 K)[1]
Boiling point decomposes[1]
Solubility in water
0.0001% (20°C)[1]
Refractive index (nD)
1.565
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
potential occupational carcinogen
GHS labelling:
Pictograms
GHS06: ToxicGHS08: Health hazardGHS09: Environmental hazard
Signal word
Danger
Hazard statements
H301, H311, H351, H410
Precautionary statements
P201, P273, P280, P301+P310+P330, P302+P352+P312[2]
Flash point 107 °C (225 °F; 380 K) (open cup)
Explosive limits 0.7–5%
Lethal dose or concentration (LD, LC):
LD50 (median dose)
590 mg/kg (rat, oral)
100 mg/kg (rabbit, oral)
430 mg/kg (mouse, oral)
300 mg/kg (rabbit, oral)
145 mg/kg (mouse, oral)
1720 mg/kg (hamster, oral)
200 mg/kg (rat, oral)[3]
NIOSH (US health exposure limits):
PEL (Permissible)
TWA 0.5 mg/m3 [skin][1]
REL (Recommended)
Ca TWA 0.5 mg/m3 [skin][1]
IDLH (Immediate danger)
100 mg/m3[1]
Safety data sheet (SDS) Chlordane (technical mixture)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)
Infobox references

Chlordane, or chlordan, is an organochlorine compound that was used as a pesticide. It is a white solid. In the United States, chlordane was used for termite-treatment of approximately 30 million homes until it was banned in 1988.[4] Chlordane was banned 10 years earlier for food crops like corn and citrus, and on lawns and domestic gardens.[5]

Like other chlorinated cyclodiene insecticides, chlordane is classified as an organic pollutant hazardous for human health. It is resistant to degradation in the environment and in humans/animals and readily accumulates in lipids (fats) of humans and animals.[6] Exposure to the compound has been linked to cancers, diabetes, and neurological disorders.

  1. ^ a b c d e f NIOSH Pocket Guide to Chemical Hazards. "#0112". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ Sigma-Aldrich Co., Chlordane (technical mixture). Retrieved on 2022-03-17.
  3. ^ "Chlordane". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  4. ^ Toxicological Profile for Chlordane, U.S. Department Of Health and Human Services, Agency for Toxic Substances and Disease Registry
  5. ^ Robert L. Metcalf "Insect Control" in Ullmann’s Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2002. doi:10.1002/14356007.a14_263
  6. ^ Agency for Toxic Substances & Disease Registry (ATSDR). Toxic Substances Portal: Chlordane. Last updated September, 2010 [online]. Available at URL: https://wwwn.cdc.gov/TSP/index.aspx?toxid=62

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Insecticide

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German cockroach

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phenyl pyrazoles. German cockroach resistance was first observed with chlordane in 1952. German cockroaches are thigmotactic, meaning they prefer confined...

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Lady Bird Lake

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1990, as a result of excessively high levels of chlordane found in the fish. Although the use of chlordane as a pesticide was banned in the United States...

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Ortho

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two substituents that occupy adjacent positions on an aromatic ring Chlordane, an organochlorine compound that was used as a pesticide Orthogonal, a...

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Organochlorine chemistry

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Joseph Regenstein

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manufactured several chlorinated insecticides including Dieldrin, Aldrin, Chlordane and Heptachlor which were the focus of Rachel Carson's book Silent Spring...

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Silent Spring

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DDT and 2,4-D, and Velsicol Chemical Company, the only manufacturer of chlordane and heptachlor, were among the first to respond. DuPont compiled an extensive...

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EPA list of extremely hazardous substances

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List of insecticides

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phosphorus chlorantraniliprole chlorbenzuron chlorbicyclen [Wikidata] chlordane chlordecone chlordimeform chlorempenthrin [Wikidata] chlorethoxyfos chlorfenapyr...

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Rachel Carson

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and 2,4-D) and Velsicol Chemical Corporation (exclusive manufacturer of chlordane and heptachlor) were among the first to respond. DuPont compiled an extensive...

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Permethrin

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Tineola bisselliella

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low concentrations practical for preservative treatment. Examples are chlordane at 2% per weight of wool, toxaphene at 0.8%, pentachlorophenol or BHC...

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Mole cricket

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vegetable crops. From the late 1940s, chlordane had been the insecticide of choice to control them, but when chlordane was banned by the U.S. EPA in the 1970s...

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Boric acid

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Rotterdam Convention

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(certain formulations) Binapacryl Captafol Carbofuran (certain formulations) Chlordane Chlordimeform Chlorobenzilate DDT Dieldrin Dinitro-ortho-cresol (DNOC)...

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IARC group 2B

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DDT

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that were chemically similar to DDT. These included aldrin, dieldrin, chlordane, heptachlor, toxaphene, and mirex. Some uses of DDT continued under the...

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Pyrethrum

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Boone Lake

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precautionary fish consumption advisories for catfish and carp due to PCB and chlordane concentrations. Children and women who are pregnant or breastfeeding are...

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Fish oil

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high levels of the toxic contaminant mercury. Dioxins, like PCBs and chlordane, as well as other chlorinated cyclodiene insecticides are also present...

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Allethrins

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The Amenta

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Ethion (Erik Miehs) on guitar, Endrin (Nathan Jenkins) on bass guitar and Chlordane (Timothy Pope) on keyboards. In 2009 the line-up had Miehs and Pope joined...

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environment beyond their intended term. Some pesticides, including aldrin, chlordane, DDT, dieldrin, endrin, heptachlor, hexachlorobenzene, mirex, and toxaphene...

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Flea treatments

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