CEACAM1 information

CEACAM1
Available structures
PDB	Ortholog search: P13688%20or%20M0R2K4 PDBe P13688,M0R2K4 RCSB
List of PDB id codes
	2GK2, 4QXW, 5DZL, 4WHD
Identifiers
Aliases	CEACAM1, BGP, BGP1, BGPI, carcinoembryonic antigen related cell adhesion molecule 1, CEA cell adhesion molecule 1
External IDs	OMIM: 109770; MGI: 1347246; HomoloGene: 128630; GeneCards: CEACAM1; OMA:CEACAM1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	42,561,234 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	25,239,282 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; mucosa of transverse colon; ; mucosa of sigmoid colon; ; rectum; ; minor salivary glands; ; jejunal mucosa; ; duodenum; ; bone marrow; ; bone marrow cells; ; appendix;
	Top expressed in
	spermatid; ; right kidney; ; zygote; ; proximal tubule; ; seminiferous tubule; ; left colon; ; secondary oocyte; ; lens; ; major salivary gland; ; parotid gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; kinase binding; protein homodimerization activity; protein phosphatase binding; protein tyrosine kinase binding; filamin binding; bile acid transmembrane transporter activity; protein dimerization activity; actin binding; calmodulin binding; molecular function; identical protein binding;
Cellular component	membrane; integral component of membrane; extracellular region; integral component of plasma membrane; extracellular exosome; T cell receptor complex; cell-cell junction; cell surface; plasma membrane; adherens junction; basal plasma membrane; apical plasma membrane; lateral plasma membrane; cell junction; transport vesicle membrane; cytoplasmic vesicle; microvillus membrane; specific granule membrane; cell projection; tertiary granule membrane;
Biological process	integrin-mediated signaling pathway; cell migration; angiogenesis; leukocyte migration; insulin catabolic process; positive regulation of vasculogenesis; cellular response to insulin stimulus; negative regulation of cytotoxic T cell degranulation; regulation of ERK1 and ERK2 cascade; regulation of homophilic cell adhesion; negative regulation of vascular permeability; regulation of endothelial cell migration; negative regulation of interleukin-1 production; homophilic cell adhesion via plasma membrane adhesion molecules; granulocyte colony-stimulating factor signaling pathway; wound healing, spreading of cells; negative regulation of hepatocyte proliferation; negative regulation of granulocyte differentiation; negative regulation of platelet aggregation; blood vessel development; negative regulation of lipid biosynthetic process; bile acid and bile salt transport; regulation of blood vessel remodeling; negative regulation of T cell receptor signaling pathway; negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target; regulation of cell growth; insulin receptor internalization; negative regulation of T cell mediated cytotoxicity; regulation of sprouting angiogenesis; negative regulation of protein kinase activity; negative regulation of fatty acid biosynthetic process; regulation of cell migration; regulation of phosphatidylinositol 3-kinase signaling; common myeloid progenitor cell proliferation; regulation of epidermal growth factor receptor signaling pathway; regulation of endothelial cell differentiation; cell adhesion; neutrophil degranulation; cell-cell adhesion via plasma-membrane adhesion molecules;
	Sources:Amigo / QuickGO
Orthologs
	634
	26367
	ENSG00000079385
	ENSMUSG00000054385
	Q3KRG8
	Q925P2
NM_001024912; NM_001184813; NM_001184815; NM_001184816; NM_001205344;
	NM_001712
	NM_001113368; NM_001113369; NM_007543
NP_001020083.1; NP_001020083; NP_001171742; NP_001171744; NP_001171745;
	NP_001192273; NP_001703
	NP_001106839; NP_001106840; NP_031569
	Wikidata
View/Edit Human	View/Edit Mouse

Carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1) also known as CD66a (Cluster of Differentiation 66a), is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000079385 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054385 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000079385 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054385 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] Cite error: The named reference entrez was invoked but never defined (see the help page).

CEACAM1 information

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