Protein-coding gene in the species Homo sapiens
CDC23 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UI9, 5A31, 5G05, 5G04
Identifiers Aliases CDC23 , ANAPC8, APC8, CUT23, cell division cycle 23External IDs OMIM: 603462; MGI: 1098815; HomoloGene: 3426; GeneCards: CDC23; OMA:CDC23 - orthologs Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.2 Start 138,187,650 bp[1] End 138,213,343 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18 B1|18 18.69 cM Start 34,764,004 bp[2] End 34,784,788 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gonad ventricular zone tibia endothelial cell rectum cerebellar hemisphere right hemisphere of cerebellum ovary islet of Langerhans left ovary
Top expressed in genital tubercle tail of embryo ventricular zone mandibular prominence medullary collecting duct superior cervical ganglion maxillary prominence abdominal wall ganglionic eminence renal corpuscle
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
ubiquitin-protein transferase activity
protein binding
Cellular component
nucleoplasm
cytosol
intracellular anatomical structure
anaphase-promoting complex
Biological process
ubiquitin-dependent protein catabolic process
regulation of exit from mitosis
regulation of mitotic metaphase/anaphase transition
cell cycle
cell division
protein K11-linked ubiquitination
metaphase
anaphase-promoting complex-dependent catabolic process
protein ubiquitination
mitotic metaphase plate congression
mitotic cell cycle
regulation of mitotic cell cycle phase transition
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 5: 138.19 – 138.21 Mb Chr 18: 34.76 – 34.78 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Cell division cycle 23 homolog (S. cerevisiae) , also known as CDC23 , is a protein that, in humans, is encoded by the CDC23 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000094880 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024370 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Entrez Gene: CDC23 cell division cycle 23 homolog (S. cerevisiae)".
Last Update: 2024-03-25T21:28:52Z
as CDC23 , is a protein that, in humans, is encoded by the CDC23 gene. The CDC23 protein shares strong similarity with Saccharomyces cerevisiae Cdc23 , a...
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Last Update: 2024-05-30T15:13:12Z
such domains include the anaphase-promoting complex (APC) subunits cdc16, cdc23 and cdc27, the NADPH oxidase subunit p67-phox, hsp90-binding immunophilins...
Word Count : 1220
Last Update: 2024-03-01T01:04:41Z
including APC5, CDC27 (APC3; MIM 116946), CDC16 (APC6; MIM 603461), and CDC23 (APC8; MIM 603462).[supplied by OMIM] ANAPC5 has been shown to interact...
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Last Update: 2024-02-01T16:52:02Z
A mutant screen of budding yeasts with mitotic arrest identified CDC16, CDC23 , and CDC27 as key genes that, when mutated, cause arrest in mitosis. G1...
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Last Update: 2024-03-25T21:32:28Z
interact with: ANAPC10, ANAPC11, ANAPC1, ANAPC4, ANAPC5, ANAPC7, CDC16, CDC20, CDC23 , CDH1, FZR1, MAD2L1 and PIN1. GRCh38: Ensembl release 89: ENSG00000004897...
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Last Update: 2023-12-22T18:21:31Z
GTPase Rac interacts with ubiquitination complex proteins Cullin-1 and CDC23 ". Int. J. Mol. Med. 8 (2): 127–33. doi:10.3892/ijmm.8.2.127. PMID 11445862...
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Last Update: 2024-03-25T21:26:44Z
eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that...
Word Count : 1291