Budesonide, sold under the brand name Pulmicort, among others, is a steroid medication.[8] It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms.[8][9] The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD).[8][10][11] The nasal spray is used for allergic rhinitis and nasal polyps.[9][12] Modified-release pills or capsules and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis, and microscopic colitis.[13][14][15]
Common side effects with the inhaled form include respiratory infections, cough, and headaches.[16] Common side effects with the pills include feeling tired, vomiting, and joint pains.[16] Serious side effects include an increased risk of infection, loss of bone strength, and cataracts.[16] Long-term use of the pill form may cause adrenal insufficiency.[16] Stopping the pills suddenly following long-term use may therefore be dangerous.[16] The inhaled form is generally safe in pregnancy.[16] Budesonide chiefly acts as a glucocorticoid.[16]
Budesonide was initially patented in 1973.[17] Commercial use as an asthma medication began in 1981.[18] It is on the World Health Organization's List of Essential Medicines.[19] Some forms are available as a generic medication.[20][21] In 2021, it was the 185th most commonly prescribed medication in the United States, with more than 2million prescriptions.[22][23]
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^"Tarpeyo- budesonide capsule, delayed release". DailyMed. Archived from the original on 25 December 2021. Retrieved 24 December 2021.
^"Pulmicort Flexhaler- budesonide aerosol, powder". DailyMed. Archived from the original on 19 September 2021. Retrieved 24 December 2021.
^"Eohilia- budesonide suspension". DailyMed. 9 February 2024. Archived from the original on 26 February 2024. Retrieved 26 February 2024.
^"Jorveza EPAR". European Medicines Agency (EMA). 17 September 2018. Archived from the original on 4 March 2023. Retrieved 3 March 2023.
^Cite error: The named reference Kinpeygo EPAR was invoked but never defined (see the help page).
^ abc"Budesonide". The American Society of Health-System Pharmacists. Archived from the original on 28 November 2015. Retrieved 2 December 2015.
^ ab"Budesonide eent". The American Society of Health-System Pharmacists. Archived from the original on 8 December 2015. Retrieved 2 December 2015.
^De Coster DA, Jones M (2014). "Tailoring of corticosteroids in COPD management". Current Respiratory Care Reports. 3 (3): 121–132. doi:10.1007/s13665-014-0084-2. PMC 4113685. PMID 25089228.
^Christophi GP, Rengarajan A, Ciorba MA (2016). "Rectal budesonide and mesalamine formulations in active ulcerative proctosigmoiditis: efficacy, tolerance, and treatment approach". Clinical and Experimental Gastroenterology. 9: 125–30. doi:10.2147/CEG.S80237. PMC 4876845. PMID 27274301.
^Rudmik L, Schlosser RJ, Smith TL, Soler ZM (July 2012). "Impact of topical nasal steroid therapy on symptoms of nasal polyposis: a meta-analysis". The Laryngoscope. 122 (7): 1431–7. doi:10.1002/lary.23259. PMID 22410935. S2CID 25637461.
^Silverman J, Otley A (July 2011). "Budesonide in the treatment of inflammatory bowel disease". Expert Review of Clinical Immunology. 7 (4): 419–28. doi:10.1586/eci.11.34. PMID 21790284. S2CID 32892611.
^Pardi DS, Tremaine WJ, Carrasco-Labra A (January 2016). "American Gastroenterological Association Institute Technical Review on the Medical Management of Microscopic Colitis". Gastroenterology. 150 (1): 247–274.e11. doi:10.1053/j.gastro.2015.11.006. PMID 26584602.
^British national formulary: BNF 58 (58 ed.). British Medical Association. 2009. pp. 56–57. ISBN 9780857111562.
^ abcdefg"Budesonide". The American Society of Health-System Pharmacists. Archived from the original on 28 November 2015. Retrieved 2 December 2015.
^Domeij B (2000). Pharmaceutical patents in Europe. The Hague: Kluwer Law International. p. 278. ISBN 9789041113481. Archived from the original on 8 December 2015.
^Hamley P (2015). Small Molecule Medicinal Chemistry: Strategies and Technologies. John Wiley & Sons. p. 390. ISBN 9781118771693. Archived from the original on 8 December 2015.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^Hamilton R (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 451. ISBN 9781284057560.
^"First Generic Drug Approvals 2023". U.S. Food and Drug Administration (FDA). 30 May 2023. Archived from the original on 30 June 2023. Retrieved 30 June 2023.
^"The Top 300 of 2021". ClinCalc. Archived from the original on 15 January 2024. Retrieved 14 January 2024.
^"Budesonide - Drug Usage Statistics". ClinCalc. Archived from the original on 29 April 2017. Retrieved 14 January 2024.
Budesonide, sold under the brand name Pulmicort, among others, is a steroid medication. It is available as an inhaler, nebulization solution, pill, nasal...
generic medication. It is also marketed in the combination formulations budesonide/formoterol and mometasone/formoterol. In November 2005, the US Food and...
randomized, placebo-controlled trials to respond well to budesonide, a glucocorticoid. Budesonide formulated to be active in the distal colon and rectum...
cromoglicate R03AK06 Salmeterol and fluticasone R03AK07 Formoterol and budesonide R03AK08 Formoterol and beclometasone R03AK09 Formoterol and mometasone...
includes medications meant to target the esophagus topically, such as budesonide, but also procedures to deal with complications, such as esophageal dilation...
July the company announced it would sell off its rights to Entocort (budesonide) to Tillotts Pharma for US$215 million. In July 2015, Genzyme announced...
other compounds may be included in irrigation fluids such as the steroid budesonide in an effort to treat chronic rhinosinusitis. Neti pots are commonly used...
available at a 75% discount compared to previous treatments. Breyna (budesonide and formoterol fumarate dihydrate inhalation aerosol): In March 2022,...
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