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Bioconjugation information


Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule.

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Bioconjugation

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Bioconjugation is a chemical strategy to form a stable covalent link between two molecules, at least one of which is a biomolecule. Recent advances in...

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Maleimide

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(Japan). Maleimide-mediated methodologies are among the most used in bioconjugation. Due to exceptionally fast reaction rates and significantly high selectivity...

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ELISA

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detected by a secondary antibody that is linked to an enzyme through bioconjugation. Between each step, the plate is typically washed with a mild detergent...

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Click chemistry

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or substrate of interest to a specific biomolecule, a process called bioconjugation. The possibility of attaching fluorophores and other reporter molecules...

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Phenylalanine

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is a protein-incorporated unnatural amino acid used as a tool for bioconjugation in the field of chemical biology. Ihlefeldt FS, Pettersen FB, von Bonin...

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Deoxyribozyme

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Keijzer JF, Dros M, Zuilhof H, Albada B (2021-09-08). "Aptamer-Assisted Bioconjugation of Tyrosine Derivatives with hemin/G-quadruplex (hGQ) DNAzyme Nucleoapzyme...

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Bioconjugate Chemistry

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is a monthly peer-reviewed scientific journal covering research in bioconjugation and the interface between man-made and biological materials. The journal...

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Bicyclononyne

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chemistry probe that enables highly efficient and completely orthogonal bioconjugation to complex macromolecules including peptides, nucleic acids and proteins...

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Hydrazone

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oxidative phosphorylation in molecular biology. Hydrazones are the basis of bioconjugation strategies. Hydrazone-based coupling methods are used in medical biotechnology...

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Azo coupling

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Chemoselective Rapid Azo-Coupling Reaction (CRACR) for Unclickable Bioconjugation". Journal of the American Chemical Society. 139 (34): 11670–11673. doi:10...

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Staudinger reaction

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Staudinger ligation, which has been called one of the most important bioconjugation methods. Two versions of the Staudinger ligation have been developed...

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SpyCatcher

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reaction through the SpyTag/SpyCatcher system. Using the Tag/Catcher pair, bioconjugation can be achieved between two recombinant proteins that would otherwise...

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Bioorthogonal chemistry

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cycloaddition has been an extremely fast and effective click reaction for bioconjugation, but it is not suitable for use in live cells due to the toxicity of...

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Neal Devaraj

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His research interests include artificial cells, lipid membranes, and bioconjugation. Devaraj attended college at the Massachusetts Institute of Technology...

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Colloidal gold

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Parak WJ (March 2010). "Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles". Philosophical Transactions. Series...

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Orthogonality

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Royzen, Maksim; Fox, Joseph M. (2008). "The Tetrazine Ligation: Fast Bioconjugation based on Inverse-electron-demand Diels-Alder Reactivity". Journal of...

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Chemical biology

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PMID 30645048. Hermanson GT (January 2013). "Chapter 3 - The Reactions of Bioconjugation". In Hermanson GT (ed.). Bioconjugate Techniques (Third ed.). Boston:...

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Allozyne

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properties and location of the 21st amino acid, allows for a variety of bioconjugation chemistries to be directed to any specific location within the protein...

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Dielectric barrier discharge

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Containing Catechol/Quinone Groups: An Alternative to Polydopamine Bioconjugation for Biomedical Applications". Advanced Healthcare Materials. 7 (11):...

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Dialkylbiaryl phosphine ligands

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Coupling reaction Organometallic chemistry Ligand Bioconjugation: Transition Metal-Mediated Bioconjugation Reactions Surry, David S.; Buchwald, Stephen L...

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