Part of the human brain, the basal forebrain structures are located in the forebrain to the front of and below the striatum. They include the ventral basal ganglia (including nucleus accumbens and ventral pallidum), nucleus basalis, diagonal band of Broca, substantia innominata, and the medial septal nucleus. These structures are important in the production of acetylcholine, which is then distributed widely throughout the brain. The basal forebrain is considered to be the major cholinergic output of the central nervous system (CNS) centred on the output of the nucleus basalis.[1] The presence of non-cholinergic neurons projecting to the cortex have been found to act with the cholinergic neurons to dynamically modulate activity in the cortex.[2]
^Goard, M; Dan, Y (November 2009). "Basal forebrain activation enhances cortical coding of natural scenes". Nature Neuroscience. 12 (11): 1444–9. doi:10.1038/nn.2402. PMC 3576925. PMID 19801988.
^Lin, SC; Brown, RE; Hussain Shuler, MG; Petersen, CC; Kepecs, A (14 October 2015). "Optogenetic Dissection of the Basal Forebrain Neuromodulatory Control of Cortical Activation, Plasticity, and Cognition". The Journal of Neuroscience. 35 (41): 13896–903. doi:10.1523/JNEUROSCI.2590-15.2015. PMC 4604228. PMID 26468190.
brain, the basalforebrain structures are located in the forebrain to the front of and below the striatum. They include the ventral basal ganglia (including...
the basal ganglia. In humans, by 5 weeks in utero it is visible as a single portion toward the front of the fetus. At 8 weeks in utero, the forebrain splits...
The medial forebrain bundle (MFB) is a neural pathway containing fibers from the basal olfactory regions, the periamygdaloid region and the septal nuclei...
group of neurons located mainly in the substantia innominata of the basalforebrain. Most neurons of the nucleus basalis are rich in the neurotransmitter...
The basal ganglia (BG) or basal nuclei are a group of subcortical nuclei found in the brains of vertebrates. In humans and other primates, differences...
inferior olive. It also projects to the thalamus, tectum, basal ganglia and basalforebrain. Basal nucleus of Meynert acts mainly on M1 receptors in the neocortex...
cases, the olfactory tubercle is identified as a round bulge along the basalforebrain anterior to the optic chiasm and posterior to the olfactory peduncle...
the pontomesencephalic tegmentum to the thalamus, tectum, basal ganglia, and basalforebrain". Brain Res. Bull. 16 (5): 603–37. doi:10.1016/0361-9230(86)90134-6...
neurons involves the basalforebrain cholinergic neurons. However, cholinergic neurons only represent about 5% of the total basalforebrain cell population...
the hippocampi, the claustrum, the various nuclei of the basal ganglia, the basalforebrain structures, and the three circumventricular organs. Brain...
junctions, preganglionic neurons of the sympathetic nervous system, the basalforebrain, and brain stem complexes are also cholinergic, as are the receptor...
basolateral amygdala, or basolateral complex, consists of the lateral, basal and accessory-basal nuclei of the amygdala. The lateral nuclei receives the majority...
locus coeruleus and ascends up into the neocortex, limbic system, and basalforebrain. Most of the neurons are projected to the posterior cortex which is...
subset of dementias. While still an area of ongoing research, the basalforebrain is implicated in the phenomenon of confabulation. People who confabulate...
that regulated sleep onset are located between the brain stem and the basalforebrain. His discoveries were not appreciated until the last two decades of...
matter. The external capsule is a route for cholinergic fibers from the basalforebrain to the cerebral cortex. The putamen separates the external capsule...
system which includes components in the brainstem, hypothalamus and basalforebrain, are the interconnected neural systems which control states of arousal...
as structures sequentially added to the forebrain in the course of evolution. According to the model, the basal ganglia are in charge of primal instincts...
involves disease progression into the basal nucleus of Meynert, a cluster of acetylcholine-rich neurons in the basalforebrain. Further, structures affected in...
brainstem and ascending through the midbrain, hypothalamus, thalamus and basalforebrain. The posterior hypothalamus plays a key role in the maintenance of...
the brain. One brain region, the subgenual anterior cingulate cortex/basalforebrain, contributes to learning altruistic behavior, especially in people...
model with damage to the basalforebrain. They proposed that the disruption of neurons that project from the basalforebrain to the MTL are responsible...
activation and arousal, and projections to acetylcholinergic neurons of the basalforebrain and dorsal pons do so indirectly, by increasing the release of acetylcholine...
sleep. Additionally, he has studied the buildup of adenosine in the basalforebrain following sleep deprivation. In the area of schizophrenia, McCarley...
November 2007). Anatomy of neuropsychiatry: the new anatomy of the basalforebrain and its implications for neuropsychiatric illness. Academic Press....
septi, Latin for 'nucleus adjacent to the septum') is a region in the basalforebrain rostral to the preoptic area of the hypothalamus. The nucleus accumbens...
(AEA) induces sleep in rats by increasing adenosine levels in the basalforebrain. These components also significantly increase slow-wave sleep during...
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